Second and third-row transition metal compounds containing benzimidazole ligands: An overview of their anticancer and antitumour activity

GV Suárez-Moreno, D Hernández-Romero… - Coordination Chemistry …, 2022 - Elsevier
The application of metal compounds in the medical field dates back to the XVI century with
some isolated reports about the therapeutic importance of metals and their compounds in …

Comprehensive review on tumour active palladium compounds and structure–activity relationships

MN Alam, F Huq - Coordination Chemistry Reviews, 2016 - Elsevier
This article provides a comprehensive review of palladium compounds that have been
evaluated for anticancer activity in vivo or in vitro from the era of discovery of cisplatin up to …

[HTML][HTML] Pt (II)-thiocarbohydrazone complex as cytotoxic agent and apoptosis inducer in Caov-3 and HT-29 Cells through the P53 and caspase-8 pathways

AA Ibrahim, MM Kareem, TH Al-Noor, T Al-Muhimeed… - Pharmaceuticals, 2021 - mdpi.com
In this study, a platinum (II) complex ([Pt (H2L)(PPh3)] complex) containing a
thiocarbohydrazone as the ligand was tested as an anti-proliferative agent against ovarian …

[HTML][HTML] FT-IR spectroscopy for the identification of binding sites and measurements of the binding interactions of important metal ions with bovine serum albumin

HA Alhazmi - Scientia Pharmaceutica, 2019 - mdpi.com
Proteins play crucial roles in the transportation and distribution of therapeutic substances,
including metal ions in living systems. Some metal ions can strongly associate, while others …

[HTML][HTML] Synthesis and Spectral Identification of Three Schiff Bases with a 2-(Piperazin-1-yl)-N-(thiophen-2-yl methylene)ethanamine Moiety Acting as Novel …

I Warad, O Ali, A Al Ali, NA Jaradat, F Hussein… - Molecules, 2020 - mdpi.com
Three new tetradentate NNNS Schiff bases (L1–L3) derived from 2-(piperidin-4-yl)
ethanamine were prepared in high yields. UV–Visible and FTIR spectroscopy were used to …

Spectral, crystal structure of novel Pyran-2-one Zwitterion Schiff derivative: Thermal, Physicochemical, DFT/HSA-interactions, enol↔ imine tautomerization and …

S Tabti, D Aggoun, D Aref, A Sawafta… - Journal of Molecular …, 2024 - Elsevier
A novel Schiff base (SB) derivative,(E)-3-(1-((2, 6-diisopropylphenyl)-imino)-ethyl)-4‑hydroxy-
6-methyl-2H-pyran-2-one, was synthesized in a high yield through the direct condensation …

Synthesis of novel bi-Zwitterion Schiff base derivate from 4‑hydroxy-2H-pyran-2-one: DFT/HSA-interactions, thermal, physicochemical, TD-DFT and optical activity

T Louaileche, S Tabti, A Djedouani, K Shalalin… - Journal of Molecular …, 2024 - Elsevier
A novel tetradentate bi-Zwitterion Schiff base (SB): 3, 3′-((1E, 1′ E)((oxybis (4, 1-
phenylene))-bis-(azanylylidene))-bis (ethan-1-yl-1-ylidene)) bis (4‑hydroxy-2H-pyran-2-one) …

pH-Responsive zinc ion regulating immunomodulatory nanoparticles for effective cancer immunotherapy

B Lim, KS Kim, K Na - Biomacromolecules, 2023 - ACS Publications
Herein, we introduce a novel approach involving the utilization of a human serum albumin-
coated zeolite imidazolate framework-8 containing a photosensitizer (HPZ) that exhibits …

Luminescent anticancer ruthenium (II)-p-cymene complexes of extended imidazophenanthroline ligands: synthesis, structure, reactivity, biomolecular interactions and …

B Sarkar, A Mondal, Y Madaan, N Roy, A Moorthy… - Dalton …, 2019 - pubs.rsc.org
Of late, cancer has become a terrible disease affecting people throughout the world.
Kee** this in mind, we tried to design drugs that are more lipophilic, target-specific, water …

Synthesis, structural characterization, antimicrobial and DNA binding studies of homoleptic zinc and copper complexes of NO Schiff bases derived from …

CE Satheesh, PR Kumar, N Shivakumar… - Inorganica Chimica …, 2019 - Elsevier
Four new homoleptic zinc (1 and 2) and copper (3 and 4) complexes of two Schiff base
ligands (L 1 H and L 2 H) derived from 2-(3, 4-dimethoxyphenyl) ethan-1-amine (5), a …