Hepatocellular carcinoma: molecular mechanism, targeted therapy, and biomarkers

Y Wang, B Deng - Cancer and Metastasis Reviews, 2023 - Springer
Hepatocellular carcinoma (HCC) is a common malignancy and one of the leading causes of
cancer-related death. The biological process of HCC is complex, with multiple factors …

Update on the applications and limitations of alpha-fetoprotein for hepatocellular carcinoma

H Hanif, MJ Ali, AT Susheela, IW Khan… - World Journal of …, 2022 - pmc.ncbi.nlm.nih.gov
Alpha-fetoprotein (AFP) is an oncofetal glycoprotein that has been used as a tumor marker
for hepatocellular carcinoma (HCC) in combination with ultrasound and other imaging …

Recent advances in systemic therapy for hepatocellular carcinoma

H Zhang, W Zhang, L Jiang, Y Chen - Biomarker Research, 2022 - Springer
Hepatocellular carcinoma (HCC) is one of the most common and lethal malignant tumors in
the world. Therapeutic options for advanced HCC are limited. Systemic treatment, especially …

AGA clinical practice guideline on systemic therapy for hepatocellular carcinoma

GL Su, O Altayar, R O'Shea, R Shah, B Estfan… - Gastroenterology, 2022 - Elsevier
Background & Aims Hepatocellular carcinoma (HCC), the most common primary liver
cancer, remains a deadly cancer, with an incidence that has tripled in the United States …

Critical appraisal of guideline recommendations on systemic therapies for advanced hepatocellular carcinoma: a review

S Cappuyns, V Corbett, M Yarchoan, RS Finn… - JAMA …, 2024 - jamanetwork.com
Importance The combination of immune checkpoint inhibitors with antiangiogenic agents
has revolutionized the treatment landscape of advanced hepatocellular carcinoma (HCC) …

[PDF][PDF] Hepatocellular carcinoma in 2021: an exhaustive update

CA Philips, S Rajesh, DC Nair, R Ahamed… - Cureus, 2021 - cureus.com
Primary liver cancer is a challenging global health concern with an estimated more than a
million persons to be affected annually by the year 2025. The commonest type is …

2022 KLCA-NCC Korea practice guidelines for the management of hepatocellular carcinoma

Korean Liver Cancer Association - Korean Journal of …, 2022 - pmc.ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is the fifth most common cancer worldwide and the fourth
most common cancer among men in South Korea, where the prevalence of chronic hepatitis …

Immune checkpoint inhibitors in kidney transplant recipients: a multicentre, single-arm, phase 1 study

RP Carroll, M Boyer, V Gebski, B Hockley… - The Lancet …, 2022 - thelancet.com
Background Most kidney transplant recipients with cancer stop or reduce
immunosuppressive therapy before starting treatment with an immune checkpoint inhibitor …

[HTML][HTML] Clinically approved combination immunotherapy: Current status, limitations, and future perspective

L Lu, M Zhan, XY Li, H Zhang, DJ Dauphars… - Current research in …, 2022 - Elsevier
Immune-checkpoint inhibitor-based combination immunotherapy has become a first-line
treatment for several major types of cancer including hepatocellular carcinoma (HCC), renal …

New insights into checkpoint inhibitor immunotherapy and its combined therapies in hepatocellular carcinoma: from mechanisms to clinical trials

H **, S Qin, J He, J **ao, Q Li… - International Journal of …, 2022 - pmc.ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is one of the most lethal tumors in China and worldwide,
although first-line therapies for HCC, such as atezolizumab and bevacizumab, have been …