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Interleaflet Coupling of Lipid Nanodomains – Insights From in vitro Systems
The plasma membrane is a complex system, consisting of two layers of lipids and proteins
compartmentalized into small structures called nanodomains. Despite the asymmetric …
compartmentalized into small structures called nanodomains. Despite the asymmetric …
The fine‐tuning of cell membrane lipid bilayers accentuates their compositional complexity
Cell membranes are now emerging as finely tuned molecular systems, signifying that re‐
evaluation of our understanding of their structure is essential. Although the idea that cell …
evaluation of our understanding of their structure is essential. Although the idea that cell …
Elastic deformations mediate interaction of the raft boundary with membrane inclusions leading to their effective lateral sorting
Liquid-ordered lipid domains represent a lateral inhomogeneity in cellular membranes.
These domains have elastic and physicochemical properties different from those of the …
These domains have elastic and physicochemical properties different from those of the …
Understanding forster resonance energy transfer in the sheet regime with DNA brick-based dye networks
Controlling excitonic energy transfer at the molecular level is a key requirement for
transitioning nanophotonics research to viable devices with the main inspiration coming …
transitioning nanophotonics research to viable devices with the main inspiration coming …
Organization of gangliosides into membrane nanodomains
Gangliosides are glycosphingolipids consisting of a ceramide base and a bulky sugar chain
that contains one or more sialic acids. This unique structure endows gangliosides with a …
that contains one or more sialic acids. This unique structure endows gangliosides with a …
Biophysical studies of lipid nanodomains using different physical characterization techniques
For the past 50 years, evidence for the existence of functional lipid domains has been
steadily accumulating. Although the notion of functional lipid domains, also known as" lipid …
steadily accumulating. Although the notion of functional lipid domains, also known as" lipid …
Ordered lipid domains assemble via concerted recruitment of constituents from both membrane leaflets
Lipid rafts serve as anchoring platforms for membrane proteins. Thus far they escaped direct
observation by light microscopy due to their small size. Here we used differently colored …
observation by light microscopy due to their small size. Here we used differently colored …
Preferential protein partitioning in biological membrane with coexisting liquid ordered and liquid disordered phase behavior: underlying design principles
Several studies now show that certain proteins exhibit selective preference toward liquid
ordered (L _o o) or toward liquid disordered (L _d d) regions of the heterogeneous …
ordered (L _o o) or toward liquid disordered (L _d d) regions of the heterogeneous …
Which Moiety Drives Gangliosides to Form Nanodomains?
D Davidović, M Kukulka, MJ Sarmento… - The Journal of …, 2023 - ACS Publications
Gangliosides are important glycosphingolipids involved in a multitude of physiological
functions. From a physicochemical standpoint, this is related to their ability to self-organize …
functions. From a physicochemical standpoint, this is related to their ability to self-organize …
The impact of the glycan headgroup on the nanoscopic segregation of gangliosides
MJ Sarmento, MC Owen, JC Ricardo, B Chmelová… - Biophysical …, 2021 - cell.com
Gangliosides form an important class of receptor lipids containing a large oligosaccharide
headgroup whose ability to self-organize within lipid membranes results in the formation of …
headgroup whose ability to self-organize within lipid membranes results in the formation of …