Signal transduction events leading to the survival, differentiation, or apoptosis of cells of the
innate or adaptive immune system must be properly coordinated to ensure the normal …

Members of the protein kinase C (PKC) family are expressed in many different cell types,
where they are known to regulate a wide variety of cellular processes that impact on cell …

1 Mast cells participate in allergies, and also in immunity and inflammation by secreting
proinflammatory cytokines. 2 Flavonoids are naturally occurring polyphenolic plant …

Introduction. Lactobacillus casei and Lactobacillus acidophilus were used to assess the anti‐
inflammatory properties in carrageenan induced acute inflammatory model. Materials and …

Androgen depletion is a key strategy for treating human prostate cancer, but the presence of
hormone-independent cells esca** treatment remains a major therapeutic challenge …

Background and purpose: Glycyrrhizae radix has been widely used as a cytoprotective,
plant‐derived medicine. We have identified a flavanoid, liquiritigenin, as an active …

Full transcriptional activity of the nuclear, DNA-bound form of NF-κB requires additional
posttranslational modifications. In this study, we systematically mapped the T cell …

Background The engagement of the T cell receptor results in actin cytoskeletal
reorganization at the immune synapse (IS) and the triggering of biochemical signaling …

Scar tissue formation is a hallmark of wound repair in adults and can chronically affect tissue
architecture and function. To understand the general phenomena, we sought to explore scar …

The potent antioxidant probiotic strains Lactobacillus mucosae AN1 and Lactobacillus
fermentum SNR1 were assessed for anti-inflammatory properties in carrageenan (acute) …