Advances of nanoparticles as drug delivery systems for disease diagnosis and treatment

R Liu, C Luo, Z Pang, J Zhang, S Ruan, M Wu… - Chinese chemical …, 2023‏ - Elsevier
Decades have passed since the first nanoparticles-base medicine was approved for human
cancer treatment, and the research and development of nanoparticles for drug delivery are …

Advances in oral drug delivery systems: Challenges and opportunities

J Lou, H Duan, Q Qin, Z Teng, F Gan, X Zhou, X Zhou - Pharmaceutics, 2023‏ - mdpi.com
The oral route is the most preferred route for systemic and local drug delivery. However, the
oral drug delivery system faces the harsh physiological and physicochemical environment of …

Glioma diagnosis and therapy: current challenges and nanomaterial-based solutions

T Li, J Li, Z Chen, S Zhang, S Li, S Wageh… - Journal of controlled …, 2022‏ - Elsevier
Glioma is often referred to as one of the most dreadful central nervous system (CNS)-specific
tumors with rapidly-proliferating cancerous glial cells, accounting for nearly half of the brain …

Interactions between nanoparticles and lymphatic systems: mechanisms and applications in drug delivery

Y Tang, B Liu, Y Zhang, Y Liu, Y Huang… - Advanced Drug Delivery …, 2024‏ - Elsevier
The lymphatic system has garnered significant attention in drug delivery research due to the
advantages it offers, such as enhancing systemic exposure and enabling lymph node …

Spatiotemporal manipulation metal–organic frameworks as oral drug delivery systems for precision medicine

Z Wang, J Chen, R Gao, L Jiang, G Zhang… - Coordination Chemistry …, 2024‏ - Elsevier
Oral drug administration is the preferred method for delivering medications due to its safety,
ease of ingestion, high patient compliance, absence of pain, and adaptability to a wide …

Tumor-associated macrophage-related strategies for glioma immunotherapy

F Tang, Y Wang, Y Zeng, A **ao, A Tong… - NPJ precision oncology, 2023‏ - nature.com
High-grade glioma is one of the deadliest primary tumors of the central nervous system.
Despite the many novel immunotherapies currently in development, it has been difficult to …

[HTML][HTML] The barrier and interface mechanisms of the brain barrier, and brain drug delivery

S Zhang, L Gan, F Cao, H Wang, P Gong, C Ma… - Brain Research …, 2022‏ - Elsevier
Three different barriers are formed between the cerebrovascular and the brain parenchyma:
the blood-brain barrier (BBB), the blood-cerebrospinal fluid barrier (BCSFB), and the …

Precise Engineering of a Se/Te Nanochaperone for Reinvigorating Cancer Radio‐Immunotherapy

Y Chang, J Huang, S Shi, L Xu, H Lin… - Advanced …, 2023‏ - Wiley Online Library
Facilely synthesized nanoradiosensitizers with well‐controlled structure and
multifunctionality are greatly desired to address the challenges of cancer radiotherapy. In …

Research progress of disulfide bond based tumor microenvironment targeted drug delivery system

W Ma, X Wang, D Zhang, X Mu - International Journal of …, 2024‏ - Taylor & Francis
Cancer poses a significant threat to human life and health. Chemotherapy is currently one of
the effective cancer treatments, but many chemotherapy drugs have cell toxicity, low …

Interactions between nanoparticles and pathological changes of vascular in Alzheimer's disease

T Lei, Z Yang, H Li, M Qin, H Gao - Advanced Drug Delivery Reviews, 2024‏ - Elsevier
Emerging evidence suggests that vascular pathological changes play a pivotal role in the
pathogenesis of Alzheimer's disease (AD). The dysfunction of the cerebral vasculature …