Virtual reality for neurorehabilitation and cognitive enhancement

DD Georgiev, I Georgieva, Z Gong, V Nanjappan… - Brain sciences, 2021 - mdpi.com
Our access to computer-generated worlds changes the way we feel, how we think, and how
we solve problems. In this review, we explore the utility of different types of virtual reality …

Excitotoxicity in ALS: overstimulation, or overreaction?

AE King, A Woodhouse, MTK Kirkcaldie… - Experimental neurology, 2016 - Elsevier
Amyotrophic lateral sclerosis (ALS) is an adult onset neurodegenerative disease that results
in motor dysfunction and death, generally from respiratory failure. 90% of ALS cases are …

Reliable activation of immature neurons in the adult hippocampus

LA Mongiat, MS Espósito, G Lombardi, AF Schinder - PloS one, 2009 - journals.plos.org
Neurons born in the adult dentate gyrus develop, mature, and connect over a long interval
that can last from six to eight weeks. It has been proposed that, during this period …

Fear conditioning and extinction differentially modify the intrinsic excitability of infralimbic neurons

E Santini, GJ Quirk, JT Porter - Journal of Neuroscience, 2008 - Soc Neuroscience
Extinction of conditioned fear is an active learning process involving inhibition of fear
expression. It has been proposed that fear extinction potentiates neurons in the infralimbic …

A threshold equation for action potential initiation

J Platkiewicz, R Brette - PLoS computational biology, 2010 - journals.plos.org
In central neurons, the threshold for spike initiation can depend on the stimulus and varies
between cells and between recording sites in a given cell, but it is unclear what mechanisms …

Homeostatic plasticity in neural development

NW Tien, D Kerschensteiner - Neural development, 2018 - Springer
Throughout life, neural circuits change their connectivity, especially during development,
when neurons frequently extend and retract dendrites and axons, and form and eliminate …

Hypothalamic oestrogen receptor alpha establishes a sexually dimorphic regulatory node of energy expenditure

JE van Veen, LG Kammel, PC Bunda, M Shum… - Nature …, 2020 - nature.com
Oestrogen receptor alpha (ERα) signalling in the ventromedial hypothalamus (VMH)
contributes to energy homeostasis by modulating physical activity and thermogenesis …

A biophysical model of dynamic balancing of excitation and inhibition in fast oscillatory large-scale networks

RG Abeysuriya, J Hadida… - PLoS computational …, 2018 - journals.plos.org
Over long timescales, neuronal dynamics can be robust to quite large perturbations, such as
changes in white matter connectivity and grey matter structure through processes including …

Adiponectin regulates contextual fear extinction and intrinsic excitability of dentate gyrus granule neurons through AdipoR2 receptors

D Zhang, X Wang, B Wang, JC Garza, X Fang… - Molecular …, 2017 - nature.com
Post-traumatic stress disorder (PTSD) is characterized by exaggerated fear expression and
impaired fear extinction. The underlying molecular and cellular mechanisms of PTSD are …

[HTML][HTML] Physiology, action potential

MH Grider, R Jessu, R Kabir - 2019 - europepmc.org
An action potential is a rapid sequence of changes in the voltage across a membrane. The
membrane voltage, or potential, is determined at any time by the relative ratio of ions …