Deep learning in Alzheimer's disease: diagnostic classification and prognostic prediction using neuroimaging data

T Jo, K Nho, AJ Saykin - Frontiers in aging neuroscience, 2019 - frontiersin.org
Deep learning, a state-of-the-art machine learning approach, has shown outstanding
performance over traditional machine learning in identifying intricate structures in complex …

Predicting reaction yields via supervised learning

AM Zuranski, JI Martinez Alvarado… - Accounts of chemical …, 2021 - ACS Publications
Conspectus Numerous disciplines, such as image recognition and language translation,
have been revolutionized by using machine learning (ML) to leverage big data. In organic …

Long-term wireless streaming of neural recordings for circuit discovery and adaptive stimulation in individuals with Parkinson's disease

R Gilron, S Little, R Perrone, R Wilt… - Nature …, 2021 - nature.com
Neural recordings using invasive devices in humans can elucidate the circuits underlying
brain disorders, but have so far been limited to short recordings from externalized brain …

Meta-analysis of fecal metagenomes reveals global microbial signatures that are specific for colorectal cancer

J Wirbel, PT Pyl, E Kartal, K Zych, A Kashani… - Nature medicine, 2019 - nature.com
Association studies have linked microbiome alterations with many human diseases.
However, they have not always reported consistent results, thereby necessitating cross …

CHAOS challenge-combined (CT-MR) healthy abdominal organ segmentation

AE Kavur, NS Gezer, M Barış, S Aslan, PH Conze… - Medical Image …, 2021 - Elsevier
Segmentation of abdominal organs has been a comprehensive, yet unresolved, research
field for many years. In the last decade, intensive developments in deep learning (DL) …

[HTML][HTML] Guidelines for develo** and reporting machine learning predictive models in biomedical research: a multidisciplinary view

W Luo, D Phung, T Tran, S Gupta, S Rana… - Journal of medical …, 2016 - jmir.org
Background As more and more researchers are turning to big data for new opportunities of
biomedical discoveries, machine learning models, as the backbone of big data analysis, are …

Gut mucosal microbiome across stages of colorectal carcinogenesis

G Nakatsu, X Li, H Zhou, J Sheng, SH Wong… - Nature …, 2015 - nature.com
Gut microbial dysbiosis contributes to the development of colorectal cancer (CRC). Here we
catalogue the microbial communities in human gut mucosae at different stages of colorectal …

Potential of fecal microbiota for early‐stage detection of colorectal cancer

G Zeller, J Tap, AY Voigt, S Sunagawa… - Molecular systems …, 2014 - embopress.org
Several bacterial species have been implicated in the development of colorectal carcinoma
(CRC), but CRC‐associated changes of fecal microbiota and their potential for cancer …

Machine learning methods in chemoinformatics

JBO Mitchell - Wiley Interdisciplinary Reviews: Computational …, 2014 - Wiley Online Library
Machine learning algorithms are generally developed in computer science or adjacent
disciplines and find their way into chemical modeling by a process of diffusion. Though …

Toward more realistic drug–target interaction predictions

T Pahikkala, A Airola, S Pietilä… - Briefings in …, 2015 - academic.oup.com
A number of supervised machine learning models have recently been introduced for the
prediction of drug–target interactions based on chemical structure and genomic sequence …