[HTML][HTML] Extracellular vesicle-loaded hydrogels for tissue repair and regeneration

Y Ju, Y Hu, P Yang, X **e, B Fang - Materials Today Bio, 2023 - Elsevier
Extracellular vesicles (EVs) are a collective term for nanoscale or microscale vesicles
secreted by cells that play important biological roles. Mesenchymal stem cells are a class of …

The evolution of commercial drug delivery technologies

AM Vargason, AC Anselmo, S Mitragotri - Nature biomedical …, 2021 - nature.com
Drug delivery technologies have enabled the development of many pharmaceutical
products that improve patient health by enhancing the delivery of a therapeutic to its target …

Multifunctional magnesium organic framework-based microneedle patch for accelerating diabetic wound healing

M Yin, J Wu, M Deng, P Wang, G Ji, M Wang, C Zhou… - Acs Nano, 2021 - ACS Publications
Diabetic wound healing is one of the major challenges in the biomedical fields. The
conventional single drug treatments have unsatisfactory efficacy, and the drug delivery …

Intradermally delivered mRNA-encapsulating extracellular vesicles for collagen-replacement therapy

Y You, Y Tian, Z Yang, J Shi, KJ Kwak, Y Tong… - Nature biomedical …, 2023 - nature.com
The success of messenger RNA therapeutics largely depends on the availability of delivery
systems that enable the safe, effective and stable translation of genetic material into …

Stimuli‐responsive nanocomposite hydrogels for biomedical applications

P Lavrador, MR Esteves, VM Gaspar… - Advanced Functional …, 2021 - Wiley Online Library
The complex tissue‐specific physiology that is orchestrated from the nano‐to the
macroscale, in conjugation with the dynamic biophysical/biochemical stimuli underlying …

[HTML][HTML] Recent progress in drug delivery

C Li, J Wang, Y Wang, H Gao, G Wei, Y Huang… - … pharmaceutica sinica B, 2019 - Elsevier
Drug delivery systems (DDS) are defined as methods by which drugs are delivered to
desired tissues, organs, cells and subcellular organs for drug release and absorption …

Delivery technologies for cancer immunotherapy

RS Riley, CH June, R Langer, MJ Mitchell - Nature reviews Drug …, 2019 - nature.com
Immunotherapy has become a powerful clinical strategy for treating cancer. The number of
immunotherapy drug approvals has been increasing, with numerous treatments in clinical …

Microneedle for transdermal drug delivery: current trends and fabrication

JH Jung, SG ** - Journal of pharmaceutical investigation, 2021 - Springer
Background Transdermal delivery has the advantage of bypassing the first-pass effect and
allowing sustained release of the drug. However, the drug delivery is limited owing to the …

Glucose-responsive insulin patch for the regulation of blood glucose in mice and minipigs

J Yu, J Wang, Y Zhang, G Chen, W Mao, Y Ye… - Nature biomedical …, 2020 - nature.com
Glucose-responsive insulin delivery systems that mimic pancreatic endocrine function could
enhance health and improve quality of life for people with type 1 and type 2 diabetes with …

Treatment of type 2 diabetes: challenges, hopes, and anticipated successes

MA Nauck, J Wefers, JJ Meier - The lancet Diabetes & endocrinology, 2021 - thelancet.com
Despite the successful development of new therapies for the treatment of type 2 diabetes,
such as glucagon-like peptide-1 (GLP-1) receptor agonists and sodium-glucose …