Major pathways involved in macrophage polarization in cancer

C Kerneur, CE Cano, D Olive - Frontiers in immunology, 2022 - frontiersin.org
Macrophages play an important role in tissue homeostasis, tissue remodeling, immune
response, and progression of cancer. Consequently, macrophages exhibit significant …

Viral nanoparticles for drug delivery, imaging, immunotherapy, and theranostic applications

YH Chung, H Cai, NF Steinmetz - Advanced Drug Delivery Reviews, 2020 - Elsevier
Viral nanoparticles (VNPs) encompass a diverse array of naturally occurring nanomaterials
derived from plant viruses, bacteriophages, and mammalian viruses. The application and …

Expansion of bacteriophages is linked to aggravated intestinal inflammation and colitis

L Gogokhia, K Buhrke, R Bell, B Hoffman, DG Brown… - Cell host & …, 2019 - cell.com
Bacteriophages are the most abundant members of the microbiota and have the potential to
shape gut bacterial communities. Changes to bacteriophage composition are associated …

[HTML][HTML] Interactions between bacteriophage, bacteria, and the mammalian immune system

JD Van Belleghem, K Dąbrowska, M Vaneechoutte… - Viruses, 2018 - mdpi.com
The human body is host to large numbers of bacteriophages (phages)–a diverse group of
bacterial viruses that infect bacteria. Phage were previously regarded as bystanders that …

Immunogenicity of bacteriophages

K Champagne-Jorgensen, T Luong, T Darby… - Trends in …, 2023 - cell.com
Hundreds of trillions of diverse bacteriophages (phages) peacefully thrive within and on the
human body. However, whether and how phages influence their mammalian hosts is poorly …

Bioinorganic hybrid bacteriophage for modulation of intestinal microbiota to remodel tumor-immune microenvironment against colorectal cancer

X Dong, P Pan, DW Zheng, P Bao, X Zeng… - Science …, 2020 - science.org
Mounting evidence suggests that the gut microbiota contribute to colorectal cancer (CRC)
tumorigenesis, in which the symbiotic Fusobacterium nucleatum (Fn) selectively increases …

The reactive oxygen species in macrophage polarization: reflecting its dual role in progression and treatment of human diseases

HY Tan, N Wang, S Li, M Hong… - … medicine and cellular …, 2016 - Wiley Online Library
High heterogeneity of macrophage is associated with its functions in polarization to different
functional phenotypes depending on environmental cues. Macrophages remain in balanced …

Disease-specific alterations in the enteric virome in inflammatory bowel disease

JM Norman, SA Handley, MT Baldridge, L Droit, CY Liu… - Cell, 2015 - cell.com
Decreases in the diversity of enteric bacterial populations are observed in patients with
Crohn's disease (CD) and ulcerative colitis (UC). Less is known about the virome in these …

[HTML][HTML] Bacteriophages in natural and artificial environments

S Batinovic, F Wassef, SA Knowler, DTF Rice… - Pathogens, 2019 - mdpi.com
Bacteriophages (phages) are biological entities that have attracted a great deal of attention
in recent years. They have been reported as the most abundant biological entities on the …

Bacteriophages and the immune system

M Popescu, JD Van Belleghem… - Annual review of …, 2021 - annualreviews.org
Bacteriophages—viruses that infect bacteria—are abundant within our bodies, but their
significance to human health is only beginning to be explored. Here, we synthesize what is …