[HTML][HTML] Long non-coding RNAs: from disease code to drug role

Y Chen, Z Li, X Chen, S Zhang - Acta Pharmaceutica Sinica B, 2021 - Elsevier
Enormous studies have corroborated that long non-coding RNAs (lncRNAs) extensively
participate in crucial physiological processes such as metabolism and immunity, and are …

[HTML][HTML] A snapshot of the PD-1/PD-L1 pathway

C Ghosh, G Luong, Y Sun - Journal of Cancer, 2021 - ncbi.nlm.nih.gov
Cancer cells can evade the attack from host immune systems via hijacking the regulatory
circuits mediated by immune checkpoints. Therefore, reactivating the antitumor immunity by …

LNCipedia 5: towards a reference set of human long non-coding RNAs

PJ Volders, J Anckaert, K Verheggen… - Nucleic acids …, 2019 - academic.oup.com
While long non-coding RNA (lncRNA) research in the past has primarily focused on the
discovery of novel genes, today it has shifted towards functional annotation of this large …

Long non-coding RNA: Classification, biogenesis and functions in blood cells

S Dahariya, I Paddibhatla, S Kumar… - Molecular …, 2019 - Elsevier
While there exist some long non-coding RNAs (lncRNAs) that are structurally similar to
mRNAs (capped, spliced, poly a tail), not all of the lncRNAs exhibit these features …

A novel hypoxic long noncoding RNA KB-1980E6. 3 maintains breast cancer stem cell stemness via interacting with IGF2BP1 to facilitate c-Myc mRNA stability

P Zhu, F He, Y Hou, G Tu, Q Li, T **, H Zeng, Y Qin… - Oncogene, 2021 - nature.com
The hostile hypoxic microenvironment takes primary responsibility for the rapid expansion of
breast cancer tumors. However, the underlying mechanism is not fully understood. Here …

Exosomal LOC85009 inhibits docetaxel resistance in lung adenocarcinoma through regulating ATG5-induced autophagy

Z Yu, H Tang, S Chen, Y **e, L Shi, S **a… - Drug Resistance …, 2023 - Elsevier
Aims This study aims at investigating the role of a neighbor long non-coding RNA (lncRNA)
of HDAC4 (LOC85009) in docetaxel (DTX) resistance of lung adenocarcinoma (LUAD) …

Clinical utility of circulating non-coding RNAs—an update

S Anfossi, A Babayan, K Pantel, GA Calin - Nature reviews Clinical …, 2018 - nature.com
Over the past decade, the amount of research and the number of publications on
associations between circulating small and long non-coding RNAs (ncRNAs) and cancer …

The human papillomavirus oncoproteins: a review of the host pathways targeted on the road to transformation

JA Scarth, MR Patterson… - Journal of General …, 2021 - microbiologyresearch.org
Persistent infection with high-risk human papillomaviruses (HR-HPVs) is the causal factor in
over 99% of cervical cancer cases, and a significant proportion of oropharyngeal and …

Global positioning system: understanding long noncoding RNAs through subcellular localization

J Carlevaro-Fita, R Johnson - Molecular cell, 2019 - cell.com
The localization of long noncoding RNAs (lncRNAs) within the cell is the primary
determinant of their molecular functions. LncRNAs are often thought of as chromatin …

The role of microRNAs, long non-coding RNAs, and circular RNAs in cervical cancer

ML Tornesello, R Faraonio, L Buonaguro… - Frontiers in …, 2020 - frontiersin.org
Prolonged infection of uterine cervix epithelium with human papillomavirus (HPV) and
constitutive expression of viral oncogenes have been recognized as the main cause of the …