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[HTML][HTML] Long non-coding RNAs: from disease code to drug role
Y Chen, Z Li, X Chen, S Zhang - Acta Pharmaceutica Sinica B, 2021 - Elsevier
Enormous studies have corroborated that long non-coding RNAs (lncRNAs) extensively
participate in crucial physiological processes such as metabolism and immunity, and are …
participate in crucial physiological processes such as metabolism and immunity, and are …
[HTML][HTML] A snapshot of the PD-1/PD-L1 pathway
Cancer cells can evade the attack from host immune systems via hijacking the regulatory
circuits mediated by immune checkpoints. Therefore, reactivating the antitumor immunity by …
circuits mediated by immune checkpoints. Therefore, reactivating the antitumor immunity by …
LNCipedia 5: towards a reference set of human long non-coding RNAs
While long non-coding RNA (lncRNA) research in the past has primarily focused on the
discovery of novel genes, today it has shifted towards functional annotation of this large …
discovery of novel genes, today it has shifted towards functional annotation of this large …
Long non-coding RNA: Classification, biogenesis and functions in blood cells
While there exist some long non-coding RNAs (lncRNAs) that are structurally similar to
mRNAs (capped, spliced, poly a tail), not all of the lncRNAs exhibit these features …
mRNAs (capped, spliced, poly a tail), not all of the lncRNAs exhibit these features …
A novel hypoxic long noncoding RNA KB-1980E6. 3 maintains breast cancer stem cell stemness via interacting with IGF2BP1 to facilitate c-Myc mRNA stability
P Zhu, F He, Y Hou, G Tu, Q Li, T **, H Zeng, Y Qin… - Oncogene, 2021 - nature.com
The hostile hypoxic microenvironment takes primary responsibility for the rapid expansion of
breast cancer tumors. However, the underlying mechanism is not fully understood. Here …
breast cancer tumors. However, the underlying mechanism is not fully understood. Here …
Exosomal LOC85009 inhibits docetaxel resistance in lung adenocarcinoma through regulating ATG5-induced autophagy
Z Yu, H Tang, S Chen, Y **e, L Shi, S **a… - Drug Resistance …, 2023 - Elsevier
Aims This study aims at investigating the role of a neighbor long non-coding RNA (lncRNA)
of HDAC4 (LOC85009) in docetaxel (DTX) resistance of lung adenocarcinoma (LUAD) …
of HDAC4 (LOC85009) in docetaxel (DTX) resistance of lung adenocarcinoma (LUAD) …
Clinical utility of circulating non-coding RNAs—an update
Over the past decade, the amount of research and the number of publications on
associations between circulating small and long non-coding RNAs (ncRNAs) and cancer …
associations between circulating small and long non-coding RNAs (ncRNAs) and cancer …
The human papillomavirus oncoproteins: a review of the host pathways targeted on the road to transformation
Persistent infection with high-risk human papillomaviruses (HR-HPVs) is the causal factor in
over 99% of cervical cancer cases, and a significant proportion of oropharyngeal and …
over 99% of cervical cancer cases, and a significant proportion of oropharyngeal and …
Global positioning system: understanding long noncoding RNAs through subcellular localization
J Carlevaro-Fita, R Johnson - Molecular cell, 2019 - cell.com
The localization of long noncoding RNAs (lncRNAs) within the cell is the primary
determinant of their molecular functions. LncRNAs are often thought of as chromatin …
determinant of their molecular functions. LncRNAs are often thought of as chromatin …
The role of microRNAs, long non-coding RNAs, and circular RNAs in cervical cancer
Prolonged infection of uterine cervix epithelium with human papillomavirus (HPV) and
constitutive expression of viral oncogenes have been recognized as the main cause of the …
constitutive expression of viral oncogenes have been recognized as the main cause of the …