Signaling mechanisms regulating endothelial permeability

D Mehta, AB Malik - Physiological reviews, 2006 - journals.physiology.org
The microvascular endothelial cell monolayer localized at the critical interface between the
blood and vessel wall has the vital functions of regulating tissue fluid balance and supplying …

Vascular cell adhesion molecule-1 expression and signaling during disease: regulation by reactive oxygen species and antioxidants

JM Cook-Mills, ME Marchese… - Antioxidants & redox …, 2011 - liebertpub.com
The endothelium is immunoregulatory in that inhibiting the function of vascular adhesion
molecules blocks leukocyte recruitment and thus tissue inflammation. The function of …

Involvement of endothelial PECAM-1/CD31 in angiogenesis.

HM DeLisser, M Christofidou-Solomidou… - The American journal …, 1997 - ncbi.nlm.nih.gov
The adhesive interactions of endothelial cells with each other and the adhesion receptors
that mediate these interactions are probably of fundamental importance to the process of …

[PDF][PDF] The biology of PECAM-1.

PJ Newman - The Journal of clinical investigation, 1997 - Am Soc Clin Investig
Platelet endothelial cell adhesion molecule-1 (PECAM-1) is a 130-kD member of the
immunoglobulin (Ig) superfamily that is expressed on the surface of circulating platelets …

Signal transduction pathways mediated by PECAM-1: new roles for an old molecule in platelet and vascular cell biology

PJ Newman, DK Newman - Arteriosclerosis, thrombosis, and …, 2003 - Am Heart Assoc
Recent studies of platelet endothelial cell adhesion molecule-1 (PECAM-1 [CD31])-deficient
mice have revealed that this molecule plays an important role in controlling the activation …

Genetic evidence for functional redundancy of platelet/endothelial cell adhesion molecule-1 (PECAM-1): CD31-deficient mice reveal PECAM-1-dependent and …

GS Duncan, DP Andrew, H Takimoto… - The Journal of …, 1999 - journals.aai.org
Platelet/endothelial cell adhesion molecule-1 (PECAM-1; CD31), a member of the Ig
superfamily, is expressed strongly at endothelial cell-cell junctions, on platelets, and on most …

Constitutive expression of E-selectin and vascular cell adhesion molecule-1 on endothelial cells of hematopoietic tissues.

KM Schweitzer, AM Dräger… - The American journal …, 1996 - ncbi.nlm.nih.gov
The first step in the homing of hematopoietic progenitor cells (HPCs) from the peripheral
blood to the bone marrow involves an adhesion molecule-dependent contact with human …

Involvement of human PECAM-1 in angiogenesis and in vitro endothelial cell migration

G Cao, CD O'Brien, Z Zhou… - … of Physiology-Cell …, 2002 - journals.physiology.org
Platelet endothelial cell adhesion molecule (PECAM)-1 has been implicated in
angiogenesis, but a number of issues remain unsettled, including the independent …

Mobilization of hematopoietic stem and progenitor cells using inhibitors of CXCR4 and VLA-4

MP Rettig, G Ansstas, JF DiPersio - Leukemia, 2012 - nature.com
Successful hematopoietic stem cell transplant requires the infusion of a sufficient number of
hematopoietic stem/progenitor cells (HSPCs) that are capable of homing to the bone marrow …

Switched at birth: a new family for PECAM-1

PJ Newman - The Journal of clinical investigation, 1999 - Am Soc Clin Investig
ITIMs are identifiable by the consensus sequence L/I/V/S–x–Y–x–x–L/V and have been
found to exist alone or in pairs within the cytoplasmic domain of an increasingly recognized …