Mammalian cortical networks are active before synaptogenesis begins in earnest, before
neuronal migration is complete, and well before an animal opens its eyes and begins to …

The cerebral cortex is the brain's outermost layer. It is responsible for processing motor and
sensory information that support high-level cognitive abilities and shape personality. Its …

During cerebral cortex development, excitatory pyramidal neurons (PNs) establish specific
projection patterns while receiving inputs from GABAergic inhibitory interneurons (INs) …

Background Exaggerated responses to sensory stimuli, a hallmark of fragile X syndrome,
contribute to anxiety and learning challenges. Sensory hypersensitivity is recapitulated in …

Spontaneous and sensory-evoked activity sculpts develo** circuits. Yet, how these activity
patterns intersect with cellular programs regulating the differentiation of neuronal subtypes is …

Altered sensory processing is a common feature in autism spectrum disorder (ASD), as
recognized in the Diagnostic and Statistical Manual of Mental Disorders (DSM‐5). Although …

Oxytocin plays an important role in brain development and is associated with various
neurotransmitter systems in the brain. Abnormalities in the production, secretion, and …

Synchronous neuronal activity is a hallmark of the develo** mouse primary
somatosensory cortex. While the patterns of synchronous neuronal activity in cortical layer …

Dysfunctional sensory systems, including altered olfactory function, have recently been
reported in patients with autism spectrum disorder (ASD). Disturbances in olfactory …

A persistent question in neuroscience is how early neuronal subtype identity is established
during the development of neuronal circuits. Despite significant progress in the …