Cognitive decline in Parkinson disease

D Aarsland, B Creese, M Politis… - Nature Reviews …, 2017 - nature.com
Dementia is a frequent problem encountered in advanced stages of Parkinson disease (PD).
In recent years, research has focused on the pre-dementia stages of cognitive impairment in …

Are dementia with Lewy bodies and Parkinson's disease dementia the same disease?

KA Jellinger, AD Korczyn - Advances in Surgical and Medical …, 2023 - taylorfrancis.com
The clinical features of dementia with Lewy bodies (DLB) and Parkinson's disease dementia
(PDD) are similar and include dementia, cognitive fluctuations, and (visual) hallucinations in …

The neurobiological basis of cognitive impairment in Parkinson's disease

GM Halliday, JB Leverenz, JS Schneider… - Movement …, 2014 - Wiley Online Library
The recent formalization of clinical criteria for Parkinson's disease with dementia (PDD)
codifies many studies on this topic, including those assessing biological correlates. These …

LRRK2 and Parkinson's disease: from genetics to targeted therapy

YL Sosero, Z Gan‐Or - Annals of clinical and translational …, 2023 - Wiley Online Library
LRRK2 variants are implicated in both familial and sporadic PD. LRRK2‐PD has a generally
benign clinical presentation and variable pathology, with inconsistent presence of Lewy …

Age-specific penetrance of LRRK2 G2019S in the Michael J. Fox Ashkenazi Jewish LRRK2 Consortium

K Marder, Y Wang, RN Alcalay, H Mejia-Santana… - Neurology, 2015 - neurology.org
Objective: Estimates of the penetrance of LRRK2 G2019S vary widely (24%–100%),
reflective of differences in ascertainment, age, sex, ethnic group, and genetic and …

[КНИГА][B] Textbook of clinical neuropsychology

JE Morgan, JH Ricker - 2016 - taylorfrancis.com
Containing 50 chapters by some of the most prominent clinical neuropsychologists, the
Textbook of Clinical Neuropsychology sets a new standard in the field in its scope, breadth …

Psychosis in Parkinson's disease: epidemiology, pathophysiology, and management

A Chang, SH Fox - Drugs, 2016 - Springer
Psychotic symptoms are common in Parkinson's disease (PD) and are associated with
poorer quality of life and increased caregiver burden. PD psychosis is correlated with …

LRRK2: cause, risk, and mechanism

C Paisán-Ruiz, PA Lewis… - Journal of Parkinson's …, 2013 - journals.sagepub.com
In 2004 it was first shown that mutations in LRRK2 can cause Parkinson's disease. This
initial discovery was quickly followed by the observation that a single particular mutation is a …

Motor and nonmotor heterogeneity of LRRK2‐related and idiopathic Parkinson's disease

C Marras, RN Alcalay, C Caspell‐Garcia… - Movement …, 2016 - Wiley Online Library
Background Parkinson's disease (PD) associated with LRRK2 mutations has been
described as similar to idiopathic PD with minor clinical differences. No study has compared …

Phenotype in parkinsonian and nonparkinsonian LRRK2 G2019S mutation carriers

C Marras, B Schüle, RP Munhoz, E Rogaeva… - Neurology, 2011 - neurology.org
Objectives: Using a family study design, we describe the motor and nonmotor phenotype in
probands with LRRK2 G2019S mutations and family members and compare these …