Mitochondria form a highly interconnected tubular network throughout the cell via a dynamic
process, with mitochondrial segments fusing and breaking apart continuously. Strong …

Mitochondria and endoplasmic reticulum (ER) are essential organelles in eukaryotic cells,
which play key roles in various biological pathways. Mitochondria are responsible for ATP …

Immunogenic cell death (ICD) based on endoplasmic reticulum (ER) stress has been widely
studied as the fundamentals of cancer immunotherapy. However, the currently available ICD …

Immunogenic cell death (ICD) represents a promising approach for enhancing tumor
therapy efficacy by inducing antitumor immune response. However, current ICD inducers …

Increasing evidence has implicated the important role of mitochondrial pathology in diabetic
cardiomyopathy (DCM), while the underlying mechanism remains largely unclear. The aim …

The ER-mitochondrial junction provides a local calcium signaling domain that is critical for
both matching energy production with demand and the control of apoptosis. Here, we …

Inter-organelle contact and communication between mitochondria and sarco/endoplasmic
reticulum (SR/ER) maintain cellular homeostasis and are profoundly disturbed during tissue …

Traditionally, researchers have believed that axons are highly dependent on their cell
bodies for long-term survival. However, recent studies point to the existence of axon …

Mitochondria typically form a reticular network radiating from the nucleus, creating an
interconnected system that supplies the cell with essential energy and metabolites. These …

The endoplasmic reticulum (ER) is the largest organelle of the cell and participates in
multiple essential functions, including the production of secretory proteins, lipid synthesis …