Development and arealization of the cerebral cortex

CR Cadwell, A Bhaduri, MA Mostajo-Radji, MG Keefe… - Neuron, 2019 - cell.com
Adult cortical areas consist of specialized cell types and circuits that support unique higher-
order cognitive functions. How this regional diversity develops from an initially uniform …

Patch-seq: Past, present, and future

M Lipovsek, C Bardy, CR Cadwell… - Journal of …, 2021 - Soc Neuroscience
Single-cell transcriptomic approaches are revolutionizing neuroscience. Integrating this
wealth of data with morphology and physiology, for the comprehensive study of neuronal …

Implementation and validation of single-cell genomics experiments in neuroscience

M Colonna, G Konopka, SA Liddelow… - Nature …, 2024 - nature.com
Single-cell or single-nucleus transcriptomics is a powerful tool for identifying cell types and
cell states. However, hypotheses derived from these assays, including gene expression …

The epigenome in neurodevelopmental disorders

J Reichard, G Zimmer-Bensch - Frontiers in Neuroscience, 2021 - frontiersin.org
Neurodevelopmental diseases (NDDs), such as autism spectrum disorders, epilepsy, and
schizophrenia, are characterized by diverse facets of neurological and psychiatric …

[HTML][HTML] Determinants of functional synaptic connectivity among amygdala-projecting prefrontal cortical neurons in male mice

Y Printz, P Patil, M Mahn, A Benjamin, A Litvin… - Nature …, 2023 - nature.com
The medial prefrontal cortex (mPFC) mediates a variety of complex cognitive functions via its
vast and diverse connections with cortical and subcortical structures. Understanding the …

[HTML][HTML] Linking transcriptomes with morphological and functional phenotypes in mammalian retinal ganglion cells

W Huang, Q Xu, J Su, L Tang, ZZ Hao, C Xu, R Liu… - Cell Reports, 2022 - cell.com
Retinal ganglion cells (RGCs) are the brain's gateway to the visual world. They can be
classified into different types on the basis of their electrophysiological, transcriptomic, or …

Patterned cPCDH expression regulates the fine organization of the neocortex

X Lv, S Li, J Li, XY Yu, X Ge, B Li, S Hu, Y Lin, S Zhang… - Nature, 2022 - nature.com
The neocortex consists of a vast number of diverse neurons that form distinct layers and
intricate circuits at the single-cell resolution to support complex brain functions. Diverse cell …

Making Ramón y Cajal proud: Development of cell identity and diversity in the cerebral cortex

DJ Di Bella, N Domínguez-Iturza, JR Brown, P Arlotta - Neuron, 2024 - cell.com
Since the beautiful images of Santiago Ramón y Cajal provided a first glimpse into the
immense diversity and complexity of cell types found in the cerebral cortex, neuroscience …

[HTML][HTML] Principles of neural stem cell lineage progression: Insights from develo** cerebral cortex

S Hippenmeyer - Current Opinion in Neurobiology, 2023 - Elsevier
How to generate a brain of correct size and with appropriate cell-type diversity during
development is a major question in Neuroscience. In the develo** neocortex, radial glial …

Formation and computational implications of assemblies in neural circuits

C Miehl, S Onasch, D Festa… - The Journal of …, 2023 - Wiley Online Library
In the brain, patterns of neural activity represent sensory information and store it in non‐
random synaptic connectivity. A prominent theoretical hypothesis states that assemblies …