Exploring the synthetic application of sulfinyl radicals

Z Zhang, X Wang, P Sivaguru, Z Wang - Organic Chemistry Frontiers, 2022 - pubs.rsc.org
Sulfinyl radicals are typical sulfur-centered π-radicals that have been known since 1957, but
their use in synthetic chemistry has been limited thus far. The majority of significant progress …

Pd-catalyzed synthesis of densely functionalized cyclopropyl vinyl sulfides reveals the origin of high selectivity in a fundamental alkyne insertion step

LT Sahharova, EG Gordeev, DB Eremin… - ACS …, 2020 - ACS Publications
Catalytic atom-economic hydrothiolation of cyclopropyl acetylenes was developed. Using
Pd/NHC complex as a precatalyst, regioselective addition of thiols to cyclopropyl acetylenes …

Phenylsulfinyl radical: Gas-phase generation, photoisomerization, and oxidation

J Xu, Z Wu, H Wan, G Deng, B Lu… - Journal of the …, 2018 - ACS Publications
Arylsulfinyl radicals are key intermediates in sulfoxide chemistry. The parent molecule,
phenylsulfinyl radical PhSO•, has been generated for the first time in the gas phase through …

Theoretical insights into photo-induced isomerization mechanisms of phenylsulfinyl radical PhSO˙

MK Liu, J Li, QS Li, ZS Li - Physical Chemistry Chemical Physics, 2022 - pubs.rsc.org
Sulfinyl radicals (R–SO˙) play important roles in lots of reactions, while the isomer oxathiyl
radicals (R–OS˙) and the isomerization between them are rarely observed due to the poor …

Amino acid oxidation: a combined study of cysteine oxo forms by IRMPD spectroscopy and simulations

D Scuderi, E Bodo, B Chiavarino… - … A European Journal, 2016 - Wiley Online Library
The redox activity of cysteine sulfur allows numerous post‐translational protein modifications
involved in the oxidative regulation of metabolism, in metal binding, and in signal …

The Trifluoromethyl Sulfinyl and Oxathiyl Radicals

Z Wu, J Xu, G Deng, X Chu, L Sokolenko… - … A European Journal, 2018 - Wiley Online Library
Two hitherto unreported sulfur‐centered radicals CF3SO. and CF3OS. were generated in
the gas phase through high‐vacuum flash pyrolyses of sulfoxide CF3S (O) X (X= CF3, Cl …

Parent Thioketene S‐Oxide H2CCSO: Gas‐Phase Generation, Structure, and Bonding Analysis

Z Wu, J Xu, L Sokolenko, YL Yagupolskii… - … A European Journal, 2017 - Wiley Online Library
The parent thioketene S‐oxide H2CCSO has been generated in the gas phase through flash
vacuum pyrolysis (ca. 1000 K) of vinyl sulfoxide H2CC (Br)− S (O) CF3 via the intermediacy …

Radical Formation in the Gas‐Phase Ozonolysis of Deprotonated Cysteine

GN Khairallah, AT Maccarone, HT Pham… - Angewandte …, 2015 - Wiley Online Library
Although the deleterious effects of ozone on the human respiratory system are well‐known,
many of the precise chemical mechanisms that both cause damage and afford protection in …

Tautomerization and dissociation of molecular peptide radical cations

X Mu, T Song, CK Siu, IK Chu - The Chemical Record, 2018 - Wiley Online Library
Radical‐mediated dissociations of peptide radical cations have intriguing unimolecular gas
phase chemistry, with cleavages of almost every bond of the peptide backbone and amino …

Graph theory-based reaction pathway searches and DFT calculations for the mechanism studies of free radical-initiated peptide sequencing mass spectrometry …

J Lee, Y Kim, WY Kim, HB Oh - Physical Chemistry Chemical Physics, 2020 - pubs.rsc.org
Graph theory-based reaction pathway searches (ACE-Reaction program) and density
functional theory calculations were performed to shed light on the mechanisms for the …