The emergence of nanomedicine drugs as a result of the fast advancement of
nanotechnology offers enormous potential for improving cancer treatment strategies. The …

Pancreatic cancer is a highly malignant and incurable disease, characterized by its
aggressive nature and high fatality rate. The most common type is pancreatic ductal …

The efficient and safe delivery of therapeutic drugs, proteins, and nucleic acids are essential
for meaningful therapeutic benefits. The field of nanomedicine shows promising implications …

Stimulator of interferon genes (STING) activation by STING agonists has been recognized as
one of the potent and promising immunotherapy strategies. However, the …

The prognosis in cases of pancreatic ductal adenocarcinoma (PDAC) with current treatment
modalities is poor owing to the highly desmoplastic tumor microenvironment (TME). Herein …

In addition to the contribution of cancer cells, the solid tumor microenvironment (TME) has a
critical role in determining tumor expansion, antitumor immunity, and the response to …

Pancreatic cancer is one of the harshest and most challenging cancers to treat, often labeled
as incurable. Chemotherapy continues to be the most popular treatment yet yields a very …

Although toll-like receptor (TLR) agonists hold great promise as immune modulators for
reprogramming the suppressive immune landscape in pancreatic ductal adenocarcinoma …

Immunotherapy has attracted widespread attention in cancer treatment and has achieved
considerable success in the clinical treatment of some tumors, but it has a low response rate …

Recent advancements in RNA therapeutics highlight the critical need for precision gene
delivery systems that target specific organs and cells. Lipid nanoparticles (LNPs) have …