Folate is a B vitamin necessary for basic biological functions, including rapid cell turnover
occurring in cancer cell proliferation. Though the role of folate as a causative versus …

Improvements in systemic cancer treatments have resulted in more patients surviving for
prolonged periods of time on treatment. This has made treatment-related toxicity and quality …

Colorectal cancer (CRC) therapy efficiency can be influenced by the microbiota in the
gastrointestinal tract. Compared with traditional intervention, prebiotics delivery into the gut …

Chronic kidney disease (CKD) is increasingly recognized as a global public health problem.
There is now convincing evidence that CKD can be detected using simple laboratory tests …

Background Cetuximab, an IgG1 chimeric monoclonal antibody against epidermal growth
factor receptor (EGFR), has activity against colorectal cancers that express EGFR. Methods …

Background Intravenous bolus fluorouracil plus leucovorin is the standard adjuvant
treatment for colon cancer. The oral fluoropyrimidine capecitabine is an established …

Purpose Both gemcitabine (GEM) and fluoropyrimidines are valuable treatment for
advanced pancreatic cancer. This open-label study was designed to compare the overall …

BACKGROUND:: Fluorouracil (FU) is an antimetabolite with activity against numerous types
of neoplasms, including those of the breast, esophagus, larynx, and gastrointestinal and …

Colon cancer is one of the leading tumours in the world and it is considered among the big
killers, together with lung, prostate and breast cancer. In the recent years very important …

Background Treatment of cancer is increasingly more effective but is associated with short
and long term side effects. Oral side effects remain a major source of illness despite the use …