Mycoplasma pneumoniae from the respiratory tract and beyond

KB Waites, L **ao, Y Liu, MF Balish… - Clinical microbiology …, 2017 - journals.asm.org
Mycoplasma pneumoniae is an important cause of respiratory tract infections in children as
well as adults that can range in severity from mild to life-threatening. Over the past several …

Antimicrobial peptides: the ancient arm of the human immune system

J Wiesner, A Vilcinskas - Virulence, 2010 - Taylor & Francis
The production of peptides and small proteins with microbicidal activity collectively called
antimicrobial peptides (AMPs) is commonly considered to be a primitive mechanism of …

International ERS/ATS guidelines on definition, evaluation and treatment of severe asthma

KF Chung, SE Wenzel, JL Brozek… - European …, 2014 - publications.ersnet.org
Severe or therapy-resistant asthma is increasingly recognised as a major unmet need. A
Task Force, supported by the European Respiratory Society and American Thoracic Society …

Steroid resistance of airway type 2 innate lymphoid cells from patients with severe asthma: the role of thymic stromal lymphopoietin

S Liu, M Verma, L Michalec, W Liu, A Sripada… - Journal of Allergy and …, 2018 - Elsevier
Background Type 2 innate lymphoid cells (ILC2s) represent an important type 2 immune
cell. Glucocorticoid regulation of human ILC2s is largely unknown. Objective We sought to …

Electronic cigarette liquid increases inflammation and virus infection in primary human airway epithelial cells

Q Wu, D Jiang, M Minor, HW Chu - PloS one, 2014 - journals.plos.org
Background/Objective The use of electronic cigarettes (e-cigarettes) is rapidly increasing in
the United States, especially among young people since e-cigarettes have been perceived …

Antimicrobial peptides of the oral cavity.

SU Gorr - Periodontology 2000, 2009 - search.ebscohost.com
The article examines the efficiency of antimicrobial peptides in preventing or treating oral
cavity. It states that most antimicrobial peptides can exhibit polymorphisms that diversify the …

SPLUNC1 regulates airway surface liquid volume by protecting ENaC from proteolytic cleavage

A Garcia-Caballero, JE Rasmussen, E Gaillard… - Proceedings of the …, 2009 - pnas.org
Many epithelia, including the superficial epithelia of the airways, are thought to secrete
“volume sensors,” which regulate the volume of the mucosal lining fluid. The epithelial Na+ …

Antimicrobial peptides in periodontal innate defense

SU Gorr - Frontiers of oral biology, 2011 - pmc.ncbi.nlm.nih.gov
Periodontal disease is an inflammatory disease initiated by the formation of mixed biofilms
on the teeth and gingival tissues. Biofilm bacteria and their toxins perturb gingival epithelial …

Modulation of innate immunity in airway epithelium for host-directed therapy

IT Myszor, GH Gudmundsson - Frontiers in immunology, 2023 - frontiersin.org
Innate immunity of the mucosal surfaces provides the first-line defense from invading
pathogens and pollutants conferring protection from the external environment. Innate …

In vitro modelling of bacterial pneumonia: a comparative analysis of widely applied complex cell culture models

L Mahieu, L Van Moll, L De Vooght… - FEMS Microbiology …, 2024 - academic.oup.com
Bacterial pneumonia greatly contributes to the disease burden and mortality of lower
respiratory tract infections among all age groups and risk profiles. Therefore, laboratory …