Cancer along with cardiovascular disease are the main causes of death in the industrialised
countries around the World. Conventional cancer treatments are losing their therapeutic …

Simple Summary Oncolytic viruses (OVs) are viruses that selectively target and kill cancer
cells while sparing normal ones. OVs are from diverse families of viruses, but naturally …

In view of the advancement in the understanding about the most diverse types of cancer and
consequently a relentless search for a cure and increased survival rates of cancer patients …

Middle East respiratory syndrome coronavirus (MERS-CoV) is a lineage C betacoronavirus,
and infections with this virus can result in acute respiratory syndrome with renal failure …

Poxviruses as a group can infect a large number of animals. However, at the level of
individual viruses, even closely related poxviruses display highly diverse host ranges and …

Viruses have been engineered for cancer therapy in a variety of ways. Approaches include
non-replicating gene therapy vectors, cancer vaccines and oncolytic viruses, but the clinical …

Twenty years of oncolytic virus development have created a field that is driven by the
potential promise of lasting impact on our cancer treatment repertoire. With the field …

Myxoma virus is a poxvirus naturally found in two American leporid (rabbit) species
(Sylvilagus brasiliensis and Sylvilagus bachmani) in which it causes an innocuous localised …

The successful replication of mammalian DNA viruses requires that they gain control of key
cellular signalling pathways that affect broad aspects of cellular macromolecular synthesis …

The ankyrin repeat (ANK) is the most common protein–protein interaction motif in nature,
and is predominantly found in eukaryotic proteins. Genome sequencing of various …