Biomaterial-based antimicrobial therapies for the treatment of bacterial infections

PP Kalelkar, M Riddick, AJ García - Nature Reviews Materials, 2022 - nature.com
The rise in antibiotic-resistant bacteria, including strains that are resistant to last-resort
antibiotics, and the limited ability of antibiotics to eradicate biofilms have necessitated the …

Lipids and lipid derivatives for RNA delivery

Y Zhang, C Sun, C Wang, KE Jankovic… - Chemical reviews, 2021 - ACS Publications
RNA-based therapeutics have shown great promise in treating a broad spectrum of
diseases through various mechanisms including knockdown of pathological genes …

Lipid polymer hybrid nanoparticles: a custom-tailored next-generation approach for cancer therapeutics

KR Gajbhiye, R Salve, M Narwade, A Sheikh… - Molecular Cancer, 2023 - Springer
Lipid-based polymeric nanoparticles are the highly popular carrier systems for cancer drug
therapy. But presently, detailed investigations have revealed their flaws as drug delivery …

The limitless future of RNA therapeutics

TR Damase, R Sukhovershin, C Boada… - … in bioengineering and …, 2021 - frontiersin.org
Recent advances in the generation, purification and cellular delivery of RNA have enabled
development of RNA-based therapeutics for a broad array of applications. RNA therapeutics …

Nanoparticle-based drug delivery in cancer therapy and its role in overcoming drug resistance

Y Yao, Y Zhou, L Liu, Y Xu, Q Chen, Y Wang… - Frontiers in molecular …, 2020 - frontiersin.org
Nanotechnology has been extensively studied and exploited for cancer treatment as
nanoparticles can play a significant role as a drug delivery system. Compared to …

Microfluidic nanoparticles for drug delivery

Y Liu, G Yang, Y Hui, S Ranaweera, CX Zhao - Small, 2022 - Wiley Online Library
Nanoparticles (NPs) have attracted tremendous interest in drug delivery in the past decades.
Microfluidics offers a promising strategy for making NPs for drug delivery due to its capability …

Lymph node metastasis in cancer progression: molecular mechanisms, clinical significance and therapeutic interventions

H Ji, C Hu, X Yang, Y Liu, G Ji, S Ge, X Wang… - … and Targeted Therapy, 2023 - nature.com
Lymph nodes (LNs) are important hubs for metastatic cell arrest and growth, immune
modulation, and secondary dissemination to distant sites through a series of mechanisms …

Recent advances in PLGA-based biomaterials for bone tissue regeneration

S **, X **a, J Huang, C Yuan, Y Zuo, Y Li, J Li - Acta biomaterialia, 2021 - Elsevier
Bone regeneration is an interdisciplinary complex lesson, including but not limited to
materials science, biomechanics, immunology, and biology. Having witnessed impressive …

Smart nanoparticles for drug delivery application: development of versatile nanocarrier platforms in biotechnology and nanomedicine

D Lombardo, MA Kiselev… - Journal of …, 2019 - Wiley Online Library
The study of nanostructured drug delivery systems allows the development of novel
platforms for the efficient transport and controlled release of drug molecules in the harsh …

A review on polymer and lipid-based nanocarriers and its application to nano-pharmaceutical and food-based systems

H Lu, S Zhang, J Wang, Q Chen - Frontiers in nutrition, 2021 - frontiersin.org
Recently, owing to well-controlled release, enhanced distribution and increased
permeability, nanocarriers used for alternative drug and food-delivery strategies have …