Host-microbe interactions influence intestinal stem cell (ISC) activity to modulate epithelial
turnover and composition. Here, we investigated the functional impacts of viral infection on …

Specific interactions of host and parasite genotypes can lead to balancing selection,
maintaining genetic diversity within populations. In order to understand the drivers of such …

Drosophila melanogaster has one of the best characterized antiviral immune responses
among invertebrates. However, relatively few easily transmitted natural virus isolates are …

Transposons are integral genome constituents that can be domesticated for host functions,
but they also represent a significant threat to genome stability. Transposon silencing is …

Piwi‐interacting RNAs (piRNAs) direct PIWI proteins to transposons to silence them, thereby
preserving genome integrity and fertility. The piRNA population can be expanded in the ** …

Drosophila remains a pre-eminent insect model system for host–virus interaction, but the
host range and fitness consequences of the drosophilid virome are poorly understood …

Metagenomic studies have demonstrated that viruses are extremely diverse and abundant
in insects, but the difficulty of isolating them means little is known about the biology of these …

Our ability to predict the emergence of novel viruses relies on there being generalizable
patterns in the susceptibilities of hosts to novel infections. Studies investigating variation in …

Transposable elements (TE) play critical roles in sha** genome evolution. Highly
repetitive TE sequences are also a major source of assembly gaps making it difficult to fully …

Establishing causal links between adaptive mutations and ecologically relevant phenotypes
is key to understanding the process of adaptation, which is a central goal in evolutionary …