Pathological perturbations of the brain are rarely confined to a single locus; instead, they
often spread via axonal pathways to influence other regions. Patterns of such disease …

Biomarkers in whichever modality are tremendously important in diagnosing of disease,
tracking disease progression and clinical trials. This applies in particular for disorders with a …

Functional and structural connectivity measures, as assessed by means of functional and
diffusion MRI, are emerging as potential intermediate biomarkers for Alzheimer disease (AD) …

Abstract Simultaneous [18F]-fluorodeoxyglucose positron emission tomography functional
magnetic resonance imaging (FDG-PET/fMRI) provides the capacity to image 2 sources of …

Cognitive, motor and psychiatric changes in prodromal Huntington's disease have nurtured
the emergent need for early interventions. Preventive clinical trials for Huntington's disease …

Resting‐state functional magnetic resonance imaging (rs‐fMRI) has the potential to shed
light on the pathophysiological mechanisms of Huntington's disease (HD), paving the way to …

Objectives To measure iron accumulation in the basal ganglia in Huntington's disease (HD)
using quantitative susceptibility map** (QSM), and to ascertain its relevance in terms of …

Trans‐neuronal propagation of mutant huntingtin protein contributes to the organised
spread of cortico‐striatal degeneration and disconnection in Huntington's disease (HD). We …

Huntington's disease is an autosomal, dominantly inherited neurodegenerative disease
caused by an expansion of the CAG repeats in exon 1 of the huntingtin gene. Neuronal …

Huntington's disease (HD) is a progressive and fatal neurodegenerative disorder caused by
an expanded trinucleotide CAG sequence in huntingtin gene (HTT) on chromosome 4. HD …