Basigin (CD147), a multifunctional transmembrane glycoprotein with various binding partners

T Muramatsu - The journal of biochemistry, 2016 - academic.oup.com
Basigin, also called CD147 or EMMPRIN, is a transmembrane glycoprotein that belongs to
the immunoglobulin superfamily. Basigin has isoforms; the common form (basigin or basigin …

Hypoxia-induced alternative splicing: the 11th Hallmark of Cancer

AR Farina, L Cappabianca, M Sebastiano… - Journal of Experimental …, 2020 - Springer
Hypoxia-induced alternative splicing is a potent driving force in tumour pathogenesis and
progression. In this review, we update currents concepts of hypoxia-induced alternative …

Exosomes from cardiomyocyte progenitor cells and mesenchymal stem cells stimulate angiogenesis via EMMPRIN

KR Vrijsen, JA Maring, SAJ Chamuleau… - Advanced …, 2016 - Wiley Online Library
To date, cellular transplantation therapy has not yet fulfilled its high expectations for cardiac
repair. A major limiting factor is lack of long‐term engraftment of the transplanted cells …

CD147 is a promising target of tumor progression and a prognostic biomarker

A Landras, C Reger de Moura, F Jouenne, C Lebbe… - Cancers, 2019 - mdpi.com
Microenvironment plays a crucial role in tumor development and progression. Cancer cells
modulate the tumor microenvironment, which also contribute to resistance to therapy …

P53: a guardian of immunity becomes its saboteur through mutation

AD Agupitan, P Neeson, S Williams, J Howitt… - International journal of …, 2020 - mdpi.com
Awareness of the importance of immunity in controlling cancer development triggered
research into the impact of its key oncogenic drivers on the immune response, as well as …

VEGF directly suppresses activation of T cells from ovarian cancer patients and healthy individuals via VEGF receptor Type 2

AC Ziogas, NG Gavalas, M Tsiatas… - … journal of cancer, 2012 - Wiley Online Library
The role of vascular endothelial growth factor (VEGF) in tumor angiogenesis is well
characterized; nevertheless, it is also a key element in promoting tumor evasion of the …

[HTML][HTML] Curcumin modulates chronic myelogenous leukemia exosomes composition and affects angiogenic phenotype via exosomal miR-21

S Taverna, S Fontana, F Monteleone, M Pucci… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Tumor derived exosomes are vesicles which contain proteins and microRNAs that mediate
cell-cell communication and are involved in angiogenesis and tumor progression. Curcumin …

Role of CD147 in the development and diagnosis of hepatocellular carcinoma

D Huang, D Rao, Q **, M Lai, J Zhang, Z Lai… - Frontiers in …, 2023 - frontiersin.org
Hepatocellular carcinoma (HCC) is the most common primary liver cancer, and the third
leading cause of cancer-related deaths worldwide. HCC is characterized by insidious onset …

Hypoxia-driven angiogenesis: role of tip cells and extracellular matrix scaffolding

S Germain, C Monnot, L Muller… - Current opinion in …, 2010 - journals.lww.com
Better understanding of the complex interplay between endothelial cells and soluble growth
factors and mechanical factors from the ECM will certainly have significant implications for …

Novel aspects of the liver microenvironment in hepatocellular carcinoma pathogenesis and development

T Tu, MA Budzinska, AE Maczurek, R Cheng… - International journal of …, 2014 - mdpi.com
Hepatocellular carcinoma (HCC) is a prevalent primary liver cancer that is derived from
hepatocytes and is characterised by high mortality rate and poor prognosis. While HCC is …