The CD8 T cell response to respiratory virus infections

ME Schmidt, SM Varga - Frontiers in immunology, 2018 - frontiersin.org
Humans are highly susceptible to infection with respiratory viruses including respiratory
syncytial virus (RSV), influenza virus, human metapneumovirus, rhinovirus, coronavirus, and …

T-cell immunity of SARS-CoV: Implications for vaccine development against MERS-CoV

WJ Liu, M Zhao, K Liu, K Xu, G Wong, W Tan, GF Gao - Antiviral research, 2017 - Elsevier
Over 12 years have elapsed since severe acute respiratory syndrome (SARS) triggered the
first global alert for coronavirus infections. Virus transmission in humans was quickly halted …

Predictors of mortality for patients with COVID-19 pneumonia caused by SARS-CoV-2: a prospective cohort study

RH Du, LR Liang, CQ Yang, W Wang… - European …, 2020 - publications.ersnet.org
The aim of this study was to identify factors associated with the death of patients with COVID-
19 pneumonia caused by the novel coronavirus SARS-CoV-2. All clinical and laboratory …

Distribution of ACE2, CD147, CD26, and other SARS‐CoV‐2 associated molecules in tissues and immune cells in health and in asthma, COPD, obesity, hypertension …

U Radzikowska, M Ding, G Tan, D Zhakparov, Y Peng… - Allergy, 2020 - Wiley Online Library
Background Morbidity and mortality from COVID‐19 caused by novel coronavirus SARS‐
CoV‐2 is accelerating worldwide, and novel clinical presentations of COVID‐19 are often …

[HTML][HTML] Acute SARS-CoV-2 infection impairs dendritic cell and T cell responses

R Zhou, KKW To, YC Wong, L Liu, B Zhou, X Li… - Immunity, 2020 - cell.com
The SARS-CoV-2 pandemic has resulted in millions of infections, yet the role of host
immune responses in early COVID-19 pathogenesis remains unclear. By investigating 17 …

T cell-mediated immune response to respiratory coronaviruses

R Channappanavar, J Zhao, S Perlman - Immunologic research, 2014 - Springer
Emerging respiratory coronaviruses such as the severe acute respiratory syndrome
coronavirus (SARS-CoV) and Middle East respiratory syndrome coronavirus (MERS-CoV) …

[HTML][HTML] Sustained cellular immune dysregulation in individuals recovering from SARS-CoV-2 infection

JK Files, S Boppana, MD Perez, S Sarkar… - The Journal of Clinical …, 2021 - jci.org
Ongoing observational clinical research has prioritized understanding the human immune
response to SARS-CoV-2 during the coronavirus disease 2019 (COVID-19) pandemic …

Selective CD8 cell reduction by SARS-CoV-2 is associated with a worse prognosis and systemic inflammation in COVID-19 patients

JM Urra, CM Cabrera, L Porras, I Ródenas - Clinical immunology, 2020 - Elsevier
The lymphopenia exhibited in patients with COVID-19 has been associated with a worse
prognosis in the development of the disease. To understand the factors associated with a …

[HTML][HTML] Cytokine release syndrome in COVID-19 patients, a new scenario for an old concern: the fragile balance between infections and autoimmunity

A Picchianti Diamanti, MM Rosado, C Pioli… - International journal of …, 2020 - mdpi.com
On 7 January 2020, researchers isolated and sequenced in China from patients with severe
pneumonitis a novel coronavirus, then called SARS-CoV-2, which rapidly spread worldwide …