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Elevated dementia risk, cognitive decline, and hippocampal atrophy in multisite chronic pain
Numerous studies have investigated the impacts of common types of chronic pain (CP) on
patients' cognitive function and observed that CP was associated with later dementia. More …
patients' cognitive function and observed that CP was associated with later dementia. More …
[HTML][HTML] A shared genetic signature for common chronic pain conditions and its impact on biopsychosocial traits
The multiple comorbidities & dimensions of chronic pain present a formidable challenge in
disentangling its aetiology. Here, we performed genome-wide association studies of 8 …
disentangling its aetiology. Here, we performed genome-wide association studies of 8 …
The genetic architecture of pain intensity in a sample of 598,339 US veterans
Chronic pain is a common problem, with more than one-fifth of adult Americans reporting
pain daily or on most days. It adversely affects quality of life and imposes substantial …
pain daily or on most days. It adversely affects quality of life and imposes substantial …
A data-driven biopsychosocial framework determining the spreading of chronic pain
Chronic pain conditions are complex syndromes characterized by a mosaic of biological,
psychological, and social factors. We derived predictive models for the number of co-existing …
psychological, and social factors. We derived predictive models for the number of co-existing …
[HTML][HTML] Shared genetic regulatory networks contribute to neuropathic and inflammatory pain: multi-omics systems analysis
F Ye, L Du, W Huang, S Wang - Biomolecules, 2022 - mdpi.com
The mechanisms of chronic pain are complex, and genetic factors play an essential role in
the development of chronic pain. Neuropathic pain (NP) and inflammatory pain (IP) are two …
the development of chronic pain. Neuropathic pain (NP) and inflammatory pain (IP) are two …
Genetic relationships between chronic pain, psychopathologies, and neuroticism
Chronic pain and psychiatric conditions have consistently demonstrated substantial overlap
in risk factors, epidemiology, and effective treatments. Previous work has identified cross …
in risk factors, epidemiology, and effective treatments. Previous work has identified cross …
[HTML][HTML] Multivariate genome-wide association study of sleep health demonstrates unity and diversity
There has been a recent push to focus sleep research less on disordered sleep and more
on the dimensional sleep health. Sleep health incorporates several dimensions of sleep …
on the dimensional sleep health. Sleep health incorporates several dimensions of sleep …
The genetic architecture of pain intensity in a sample of 598,339 US veterans
H Kranzler, S Toikumo, R Vickers-Smith, Z **wala… - 2023 - researchsquare.com
Chronic pain is a common problem, with more than one-fifth of adult Americans reporting
pain daily or on most days. It adversely affects quality of life and imposes substantial …
pain daily or on most days. It adversely affects quality of life and imposes substantial …