Epithelial cells are the most common cell type in all animals, forming the sheets and tubes
that compose most organs and tissues. Apical–basal polarity is essential for epithelial cell …

The blood-brain barrier (BBB) allows the brain to selectively import nutrients and energy
critical to neuronal function while simultaneously excluding neurotoxic substances from the …

Spermatogenesis is the cellular process by which spermatogonia develop into mature
spermatids within seminiferous tubules, the functional unit of the mammalian testis, under …

Cell-cell adhesions are critical for the development and maintenance of tissues. Present at
sites of cell-cell contact are the adherens junctions and tight junctions. The adherens …

abstract The blood-brain barrier (BBB) is a highly complex and dynamic barrier. It is formed
by an interdependent network of brain capillary endothelial cells, endowed with barrier …

The intestinal epithelial monolayer forms a transcellular and paracellular barrier that
separates luminal contents from the interstitium. The paracellular barrier consists of a highly …

Tight junctions are complex supramolecular entities composed of integral membrane
proteins, membrane-associated and soluble cytoplasmic proteins engaging in an intricate …

The Blood–brain barrier (BBB), present at the level of the endothelium of cerebral blood
vessels, selectively restricts the blood-to-brain paracellular diffusion of compounds; it is …

The homeostasis of the central nervous system (CNS) is ensured by the endothelial,
epithelial, mesothelial and glial brain barriers, which strictly control the passage of …

The blood-brain barrier (BBB) is formed by the endothelial cells of cerebral microvessels,
providing a dynamic interface between the peripheral circulation and the central nervous …