Individuals with spinal cord injury (SCI) can face decades with permanent disabilities.
Advances in clinical management have decreased morbidity and improved outcomes, but …

The review demonstrates that control of posture and locomotion is provided by systems
across the caudal-to-rostral extent of the neuraxis. A common feature of the neuroanatomic …

Axon regeneration can be induced across anatomically complete spinal cord injury (SCI),
but robust functional restoration has been elusive. Whether restoring neurological functions …

Contusive spinal cord injury leads to a variety of disabilities owing to limited neuronal
regeneration and functional plasticity. It is well established that an upregulation of glial …

The purpose of this review is to discuss the achievements and perspectives regarding
rehabilitation of sensorimotor functions after spinal cord injury. In the first part we discuss …

A major hurdle for functional recovery after both spinal cord injury and cortical stroke is the
limited regrowth of the axons in the corticospinal tract (CST) that originate in the motor cortex …

Movement is accomplished by the controlled activation of motor unit populations. Our
understanding of motor unit physiology has been derived from experimental work on the …

After spinal cord injury (SCI), various sensorimotor functions can recover, ranging from
simple spinal reflexes to more elaborate motor patterns, such as locomotion. Locomotor …

Blood vessels in the central nervous system (CNS) are controlled by neuronal activity. For
example, widespread vessel constriction (vessel tone) is induced by brainstem neurons that …

Spasticity is defined clinically by increased muscle tone and tendon jerk hyperreflexia in
patients who are at rest. However, the excitability of spinal circuits changes during …