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Novel and emerging treatments for major depression
Depression is common, costly, debilitating, and associated with increased risk of suicide. It is
one of the leading global public health problems. Although existing available …
one of the leading global public health problems. Although existing available …
Psychedelic therapy for depressive symptoms: A systematic review and meta-analysis
Background Psychedelic therapy shows promise for Major Depressive Disorder, especially
when treatment-resistant, as well as life-threatening illness distress. The objective of this …
when treatment-resistant, as well as life-threatening illness distress. The objective of this …
Adverse events in clinical treatments with serotonergic psychedelics and MDMA: A mixed-methods systematic review
JJ Breeksema, BW Kuin, J Kamphuis… - Journal of …, 2022 - journals.sagepub.com
Introduction: Small-scale clinical studies with psychedelic drugs have shown promising
results for the treatment of several mental disorders. Before psychedelics become registered …
results for the treatment of several mental disorders. Before psychedelics become registered …
Psychedelic drugs: neurobiology and potential for treatment of psychiatric disorders
FX Vollenweider, KH Preller - Nature Reviews Neuroscience, 2020 - nature.com
Renewed interest in the use of psychedelics in the treatment of psychiatric disorders
warrants a better understanding of the neurobiological mechanisms underlying the effects of …
warrants a better understanding of the neurobiological mechanisms underlying the effects of …
History repeating: guidelines to address common problems in psychedelic science
Research in the last decade has expressed considerable optimism about the clinical
potential of psychedelics for the treatment of mental disorders. This optimism is reflected in …
potential of psychedelics for the treatment of mental disorders. This optimism is reflected in …
Blinding and expectancy confounds in psychedelic randomized controlled trials
SD Muthukumaraswamy, A Forsyth… - Expert review of clinical …, 2021 - Taylor & Francis
Introduction: There is increasing interest in the potential for psychedelic drugs such as
psilocybin, LSD and ketamine to treat several mental health disorders, with a growing …
psilocybin, LSD and ketamine to treat several mental health disorders, with a growing …
Psychedelics and psychedelic-assisted psychotherapy
CM Reiff, EE Richman, CB Nemeroff… - American Journal of …, 2020 - psychiatryonline.org
Objective: The authors provide an evidenced-based summary of the literature on the clinical
application of psychedelic drugs in psychiatric disorders. Methods: Searches of PubMed and …
application of psychedelic drugs in psychiatric disorders. Methods: Searches of PubMed and …
Therapeutic effects of classic serotonergic psychedelics: A systematic review of modern‐era clinical studies
KAA Andersen, R Carhart‐Harris… - Acta Psychiatrica …, 2021 - Wiley Online Library
Objective To conduct a systematic review of modern‐era (post‐millennium) clinical studies
assessing the therapeutic effects of serotonergic psychedelics drugs for mental health …
assessing the therapeutic effects of serotonergic psychedelics drugs for mental health …
Psychedelics promote structural and functional neural plasticity
C Ly, AC Greb, LP Cameron, JM Wong, EV Barragan… - Cell reports, 2018 - cell.com
Atrophy of neurons in the prefrontal cortex (PFC) plays a key role in the pathophysiology of
depression and related disorders. The ability to promote both structural and functional …
depression and related disorders. The ability to promote both structural and functional …
Psilocybin with psychological support for treatment-resistant depression: six-month follow-up
Rationale Recent clinical trials are reporting marked improvements in mental health
outcomes with psychedelic drug-assisted psychotherapy. Objectives Here, we report on …
outcomes with psychedelic drug-assisted psychotherapy. Objectives Here, we report on …