Gut microbiome and depression: what we know and what we need to know

G Winter, RA Hart, RPG Charlesworth… - Reviews in the …, 2018 - degruyter.com
Gut microbiome diversity has been strongly associated with mood-relating behaviours,
including major depressive disorder (MDD). This association stems from the recently …

The recent progress in animal models of depression

Q Wang, MA Timberlake II, K Prall, Y Dwivedi - Progress in Neuro …, 2017 - Elsevier
Major depression disorder (MDD) is a debilitating mental illness with significant morbidity
and mortality. Despite the growing number of studies that have emerged, the precise …

Stress, serotonin, and hippocampal neurogenesis in relation to depression and antidepressant effects

I Mahar, FR Bambico, N Mechawar… - … & Biobehavioral Reviews, 2014 - Elsevier
Chronic stressful life events are risk factors for develo** major depression, the
pathophysiology of which is strongly linked to impairments in serotonin (5-HT) …

May the force be with you: the light and dark sides of the microbiota–gut–brain axis in neuropsychiatry

E Sherwin, KV Sandhu, TG Dinan, JF Cryan - CNS drugs, 2016 - Springer
The role of the gut microbiota in health and disease is becoming increasingly recognized.
The microbiota–gut–brain axis is a bi-directional pathway between the brain and the …

The ascent of mouse: advances in modelling human depression and anxiety

JF Cryan, A Holmes - Nature reviews Drug discovery, 2005 - nature.com
Psychiatry has proven to be among the least penetrable clinical disciplines for the
development of satisfactory in vivo model systems for evaluating novel treatment …

Altered colonic function and microbiota profile in a mouse model of chronic depression

AJ Park, J Collins, PA Blennerhassett… - …, 2013 - Wiley Online Library
Background Depression often coexists with the irritable bowel syndrome (IBS) which is
characterized by alterations in gut function. There is emerging evidence that the microbial …

The role of the microbiome-brain-gut axis in the pathogenesis of depressive disorder

E Młynarska, J Gadzinowska, J Tokarek, J Forycka… - Nutrients, 2022 - mdpi.com
The role of gut microbiota and its association with the central nervous system via the
microbiome-brain-gut axis has been widely discussed in the literature. The aim of this review …

Revisiting the serotonin hypothesis: implications for major depressive disorders

M Fakhoury - Molecular neurobiology, 2016 - Springer
Major depressive disorder (MDD) is a heritable neuropsychiatric disease associated with
severe changes at cellular and molecular levels. Its diagnosis mainly relies on the …

[HTML][HTML] Effects of inhaled Linalool in anxiety, social interaction and aggressive behavior in mice

VM Linck, AL da Silva, M Figueiró, EB Caramao… - Phytomedicine, 2010 - Elsevier
Aromatherapy uses essential oils (EOs) for several medical purposes, including relaxation.
The association between the use of aromas and a decrease in anxiety could be a valuable …

Animal models of mood disorders: recent developments

JF Cryan, DA Slattery - Current opinion in psychiatry, 2007 - journals.lww.com
Endophenotype-based modelling of depression and bipolar illness is opening up more
tractable avenues for understanding the neurobiological and genetic bases of these …