Harnessing nanomaterials for cancer sonodynamic immunotherapy

S Liang, J Yao, D Liu, L Rao, X Chen… - Advanced …, 2023 - Wiley Online Library
Immunotherapy has made remarkable strides in cancer therapy over the past decade.
However, such emerging therapy still suffers from the low response rates and immune …

Emerging sonodynamic therapy‐based nanomedicines for cancer immunotherapy

Y Yang, J Huang, M Liu, Y Qiu, Q Chen… - Advanced …, 2023 - Wiley Online Library
Cancer immunotherapy effect can be greatly enhanced by other methods to induce
immunogenic cell death (ICD), which has profoundly affected immunotherapy as a highly …

Extracellular vesicles‐derived hybrid nanoplatforms for amplified CD47 blockade‐based cancer immunotherapy

L Tang, Y Yin, Y Cao, C Fu, H Liu, J Feng… - Advanced …, 2023 - Wiley Online Library
Immunomodulation of tumor‐associated macrophages (TAMs) into tumor‐inhibiting M1‐like
phenotype is a promising but challenging strategy. Cleverly, tumor cells overexpress CD47 …

Reactive oxygen species-powered cancer immunotherapy: Current status and challenges

M He, M Wang, T Xu, M Zhang, H Dai, C Wang… - Journal of Controlled …, 2023 - Elsevier
Reactive oxygen species (ROS) are crucial signaling molecules that can arouse immune
system. In recent decades, ROS has emerged as a unique therapeutic strategy for malignant …

Peptide‐Appended Nanosonosensitizers Targeting Tumor Glycolysis for Synergistic Sonodynamic–Immunometabolic Therapy of Spinal‐Metastasized Tumors

Z Chen, L Chen, Y Ma, Y Liu, Q Zhang, H Qin… - Advanced …, 2023 - Wiley Online Library
Despite recent advancements in cancer immunotherapy, challenges have yet to be
surmounted to achieve two major goals of magnifying antitumor immunity and remodeling …

Genetically Engineered‐Cell‐Membrane Nanovesicles for Cancer Immunotherapy

Q Cheng, Y Kang, B Yao, J Dong, Y Zhu… - Advanced …, 2023 - Wiley Online Library
The advent of immunotherapy has marked a new era in cancer treatment, offering significant
clinical benefits. Cell membrane as drug delivery materials has played a crucial role in …

Construction of Long‐Wavelength Emissive Organic Nanosonosensitizer Targeting Mitochondria for Precise and Efficient In Vivo Sonotherapy

X Zhang, C Li, Y Zhang, X Guan, L Mei… - Advanced Functional …, 2022 - Wiley Online Library
As a modern biomedical therapeutic modality, sonodynamic therapy (SDT) presents unique
advantages, including superior tissue penetration capability, temporal–spatial controllability …

Immunomodulatory‐Photodynamic Nanostimulators for Invoking Pyroptosis to Augment Tumor Immunotherapy

W Qiu, W Su, J Xu, M Liang, X Ma, P Xue… - Advanced …, 2022 - Wiley Online Library
Cancer immunotherapy is restricted to immune resistance caused by immunosuppressive
tumor microenvironment. Pyroptosis involved in antitumor immunotherapy as a new …

[HTML][HTML] Immune-regulating camouflaged nanoplatforms: A promising strategy to improve cancer nano-immunotherapy

BQ Chen, Y Zhao, Y Zhang, YJ Pan, HY **a… - Bioactive Materials, 2023 - Elsevier
Although nano-immunotherapy has advanced dramatically in recent times, there remain two
significant hurdles related to immune systems in cancer treatment, such as (namely) …

Endogenous/exogenous stimulies inspired polyprodrug nano-inducer switches pyroptosis path for promoting antitumor immunity

X Ma, W Su, M Ye, Y Gao, W Qiu, M Liang, P Xue… - Nano Today, 2023 - Elsevier
Pyroptosis-based nanomedicine shows great potential to unchoke the bottlenecks of cancer
immunotherapy, but hindered by precise and specific regulation of pyroptosis in tumor cells …