Renal cell carcinoma as a metabolic disease: an update on main pathways, potential biomarkers, and therapeutic targets

NA di Meo, F Lasorsa, M Rutigliano, D Loizzo… - International Journal of …, 2022 - mdpi.com
Clear cell renal cell carcinoma (ccRCC) is the most frequent histological kidney cancer
subtype. Over the last decade, significant progress has been made in identifying the genetic …

[HTML][HTML] Kidney injury molecule 1 (KIM-1): a multifunctional glycoprotein and biological marker

ТА Karmakova, NS Sergeeva, КY Kanukoev… - Современные …, 2021 - cyberleninka.ru
KIM-1 (kidney injury molecule 1) is a transmembrane glycoprotein also known as HAVcr-1
and TIM-1 belongs to the T-cell immunoglobulin and mucin domain family (TIM) of proteins …

[HTML][HTML] Regulated necrosis and failed repair in cisplatin-induced chronic kidney disease

SI Landau, X Guo, H Velazquez, R Torres, E Olson… - Kidney international, 2019 - Elsevier
Cisplatin is an effective chemotherapeutic agent, but significant nephrotoxicity limits its
clinical use. Despite extensive investigation of the acute cellular and molecular responses to …

Cell state of origin impacts development of distinct endometriosis-related ovarian carcinoma histotypes

I Beddows, H Fan, K Heinze, BK Johnson, A Leonova… - Cancer Research, 2024 - AACR
Clear cell ovarian carcinoma (CCOC) and endometrioid ovarian carcinoma (ENOC) are
ovarian carcinoma histotypes, which are both thought to arise from ectopic endometrial (or …

[HTML][HTML] Laparoscopic versus open radical nephrectomy for renal cell carcinoma: a systematic review and meta-analysis

G Liu, Y Ma, S Wang, X Han, D Gao - Translational oncology, 2017 - Elsevier
BACKGROUND: The aim of this study is to summarize and quantify the current evidence on
the therapeutic efficacy of laparoscopic radical nephrectomy (LRN) compared with open …

Sarcopenia and the modified Glasgow prognostic score are significant predictors of survival among patients with metastatic renal cell carcinoma who are receiving first …

H Ishihara, T Kondo, K Omae, T Takagi, J Iizuka… - Targeted …, 2016 - Springer
Background Cancer cachexia is associated with patient outcomes. Objective The objective
was to evaluate the effect of cachexia on survival among patients with metastatic renal cell …

Early detection of kidney cancer using urinary proteins: a truly non‐invasive strategy

JG Flitcroft, J Verheyen, T Vemulkar… - BJU …, 2022 - Wiley Online Library
Objectives To review urinary protein biomarkers as potential non‐invasive, easily
obtainable, early diagnostic tools in renal cell carcinoma (RCC). Methods A PubMed …

Renal cell carcinoma: molecular aspects

A Kumar, N Kumari, V Gupta, R Prasad - Indian Journal of Clinical …, 2018 - Springer
Renal cell carcinoma is the most common form of the kidney cancer accounting for more
than 85% of the cases of which clear cell renal cell carcinoma (ccRCC) is the major …

[HTML][HTML] Overriding TKI resistance of renal cell carcinoma by combination therapy with IL-6 receptor blockade

K Ishibashi, T Haber, I Breuksch, S Gebhard, T Sugino… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Metastatic renal cell carcinoma (RCC) is a tumor entity with poor prognosis due to limited
therapy options. Tyrosine kinase inhibitors (TKI) represent the standard of care for RCCs …

The role of p-STAT3 as a prognostic and clinicopathological marker in colorectal cancer: a systematic review and meta-analysis

K Ji, M Zhang, Q Chu, Y Gan, H Ren, L Zhang… - PLoS …, 2016 - journals.plos.org
Objective High expression of phosphorylated signal transducer and activator of transcription
3 (p-STAT3) has been detected in a variety of human tumors. However, the association of …