The skeletal system is responsible for weight-bearing, organ protection, and movement.
Bone diseases caused by trauma, infection, and aging can seriously affect a patient's quality …

Bone regeneration repairs bone tissue lost due to trauma, fractures, and tumors, or absent
due to congenital disorders. The extracellular matrix (ECM) is an intricate dynamic bio …

Current clinical approaches to osteoporosis primarily target osteoclast biology, overlooking
the synergistic role of bone cells, immune cells, cytokines, and inorganic components in …

This review summarises current understanding of how bone is sculpted through adaptive
processes, designed to meet the mechanical challenges it faces in everyday life and athletic …

Osteoporosis affects about 200 million people worldwide and is a silent disease until a
fracture occurs. Management of osteoporosis is still a challenge that warrants further studies …

Understanding how bones are innately designed, robustly developed and delicately
maintained through intricate anatomical features and physiological processes across the …

The availability of wearable devices (WDs) to collect biometric information and their use
during activities of daily living is significantly increasing in the general population. These …

It is unclear how physical activity stimulates new bone synthesis. We explored whether irisin,
a newly discovered myokine released upon physical activity, displays anabolic actions on …

Rationale: Osteoporosis is a severe bone disorder that is a threat to our aging population.
Excessive osteoclast formation and bone resorption lead to changes in trabecular bone …

Polyetheretherketone (PEEK) has been an alternative material for titanium in bone defect
repair, but its clinical application is limited by its poor osseointegration. In this study, a …