Chemotherapy is one of the prevailing methods used to treat malignant tumours, but the
outcome and prognosis of tumour patients are not optimistic. Cancer cells gradually …

Cancer is one of the main causes of death throughout the world. The anticancer agents are
indispensable for the treatment of various cancers, but most of them currently on the market …

The development of versatile nanotheranostic platforms that integrate both diagnostic and
therapeutic functions have always been an intractable challenge in precise cancer …

Although technically a member of the Inhibitor of Apoptosis (IAP) gene family, survivin has
consistently defied assumptions, refuted predictions and challenged paradigms. Despite its …

Survivin is an anti-apoptotic protein belonging to the inhibitor of apoptosis protein (IAP)
family. It is involved in the regulation of important physiological and pathological processes …

The overexpression of survivin in breast cancer cells is an important factor of paclitaxel
(PTX) resistance in breast cancer. To overcome PTX resistance and improve the antitumor …

Glycolysis has been reported to be critical for cancer stem cells (CSCs), which are
associated with tumor chemoresistance, metastasis and recurrence. Thus, selectively …

Combined chemotherapeutic treatment is the method of choice for advanced and metastatic
gastric tumors. However, resistance to chemotherapeutic agents is one of the main …

Multidrug resistance (MDR) remains one of the most significant obstacles in breast cancer
treatment, and this process often involves dysregulation of a great number of microRNAs …

The poor prognosis of pancreatic cancer patients signifies a need for radically new
therapeutic strategies. Tumor-targeted oncolytic viruses have emerged as attractive …