Hepatitis C treatment as prevention: evidence, feasibility, and challenges

B Hajarizadeh, J Grebely, M Martinello… - The lancet …, 2016 - thelancet.com
The advent of interferon-free direct-acting antiviral therapy for hepatitis C virus (HCV)
infection has heightened discussion of treatment as prevention. Rapid scale-up in many …

Hepatitis B: current status of therapy and future therapies

E Spyrou, CI Smith, MG Ghany - Gastroenterology Clinics, 2020 - gastro.theclinics.com
Chronic hepatitis B virus (HBV) infection is a substantial global public health problem.
Despite the availability of a protective vaccine for more than 3 decades, the prevalence of …

[PDF][PDF] 17‐beta hydroxysteroid dehydrogenase 13 is a hepatic retinol dehydrogenase associated with histological features of nonalcoholic fatty liver disease

Y Ma, OV Belyaeva, PM Brown, K Fujita, K Valles… - …, 2019 - Wiley Online Library
Nonalcoholic fatty liver disease (NAFLD) is a common cause of chronic liver disease. A
single‐nucleotide polymorphism (SNP), rs6834314, was associated with serum liver …

Hepatitis C virus treatment as prevention in an extended network of people who inject drugs in the USA: a modelling study

A Zelenev, J Li, A Mazhnaya, S Basu… - The Lancet Infectious …, 2018 - thelancet.com
Background Chronic infections with hepatitis C virus (HCV) and HIV are highly prevalent in
the USA and concentrated in people who inject drugs. Treatment as prevention with highly …

Scaling‐up HCV prevention and treatment interventions in rural United States—model projections for tackling an increasing epidemic

H Fraser, J Zibbell, T Hoerger, S Hariri, C Vellozzi… - …, 2018 - Wiley Online Library
Background and aims Effective strategies are needed to address dramatic increases in
hepatitis C virus (HCV) infection among people who inject drugs (PWID) in rural settings of …

An educate, test, and treat programme towards elimination of hepatitis C infection in Egypt: a community-based demonstration project

G Shiha, AM Metwally, R Soliman… - The Lancet …, 2018 - thelancet.com
Background Egypt has one of the highest prevalences and burdens of hepatitis C virus
(HCV) worldwide, and a large government treatment programme. However, identifying and …

Estimating the year each state in the United States will achieve the World Health Organization's elimination targets for hepatitis C

M Sulkowski, WH Cheng, S Marx… - Advances in …, 2021 - Springer
Introduction Although hepatitis C virus (HCV) infection remains a major clinical, economic,
and societal burden, the development of curative antiviral therapy may accelerate the path …

Treat chronic hepatitis C virus infection in decompensated cirrhosis–pre‐or post‐liver transplantation? The ironic conundrum in the era of effective and well‐tolerated …

C Bunchorntavakul, KR Reddy - Journal of viral hepatitis, 2016 - Wiley Online Library
The management of hepatitis C virus (HCV) infection in patients with decompensated
cirrhosis has evolved dramatically over the past few years mainly due to the availability of all …

Are leprosy case numbers reliable?

CG Salgado, JG Barreto… - The Lancet …, 2018 - pubmed.ncbi.nlm.nih.gov
Are leprosy case numbers reliable? Are leprosy case numbers reliable? Lancet Infect Dis.
2018 Feb;18(2):135-137. doi: 10.1016/S1473-3099(18)30012-4. Authors Claudio Guedes …

Novel hepatitic C virus (HCV) diagnosis and treatment delivery systems: facilitating HCV elimination by thinking outside the clinic

S Bajis, TL Applegate, J Grebely… - The Journal of …, 2020 - academic.oup.com
Abstract The World Health Organization has set a goal to eliminate hepatitis C virus (HCV)
infection as public health threat by 2030. Although the advent of highly effective and …