An updated review on marine anticancer compounds: The use of virtual screening for the discovery of small-molecule cancer drugs
Marine secondary metabolites are a promising source of unexploited drugs that have a wide
structural diversity and have shown a variety of biological activities. These compounds are …
structural diversity and have shown a variety of biological activities. These compounds are …
Marine fungi: A source of potential anticancer compounds
Metabolites from marine fungi have hogged the limelight in drug discovery because of their
promise as therapeutic agents. A number of metabolites related to marine fungi have been …
promise as therapeutic agents. A number of metabolites related to marine fungi have been …
A RaPID way to discover nonstandard macrocyclic peptide modulators of drug targets
T Passioura, H Suga - Chemical Communications, 2017 - pubs.rsc.org
Studies of the fundamental nature of RNA catalysis and the potential mechanism of a shift
from the “RNA world” to proteinaceous life lead us to identify a set of ribozymes (flexizymes) …
from the “RNA world” to proteinaceous life lead us to identify a set of ribozymes (flexizymes) …
Cyclic peptides in pipeline: what future for these great molecules?
L Costa, E Sousa, C Fernandes - Pharmaceuticals, 2023 - mdpi.com
Cyclic peptides are molecules that are already used as drugs in therapies approved for
various pharmacological activities, for example, as antibiotics, antifungals, anticancer, and …
various pharmacological activities, for example, as antibiotics, antifungals, anticancer, and …
Nonribosomal peptides from marine microbes and their antimicrobial and anticancer potential
Marine environments are largely unexplored and can be a source of new molecules for the
treatment of many diseases such as malaria, cancer, tuberculosis, HIV etc. The Marine …
treatment of many diseases such as malaria, cancer, tuberculosis, HIV etc. The Marine …
Current status and future prospects of marine natural products (MNPs) as antimicrobials
A Choudhary, LM Naughton, I Montánchez… - Marine drugs, 2017 - mdpi.com
The marine environment is a rich source of chemically diverse, biologically active natural
products, and serves as an invaluable resource in the ongoing search for novel …
products, and serves as an invaluable resource in the ongoing search for novel …
Marine pharmacology in 2016–2017: Marine compounds with antibacterial, antidiabetic, antifungal, anti-inflammatory, antiprotozoal, antituberculosis and antiviral …
AMS Mayer, AJ Guerrero, AD Rodríguez… - Marine drugs, 2021 - mdpi.com
The review of the 2016–2017 marine pharmacology literature was prepared in a manner
similar as the 10 prior reviews of this series. Preclinical marine pharmacology research …
similar as the 10 prior reviews of this series. Preclinical marine pharmacology research …
Peptides, peptidomimetics, and polypeptides from marine sources: a wealth of natural sources for pharmaceutical applications
Nature provides a variety of peptides that are expressed in most living species. Evolutionary
pressure and natural selection have created and optimized these peptides to bind to …
pressure and natural selection have created and optimized these peptides to bind to …
The landscape of natural product diversity and their pharmacological relevance from a focus on the Dictionary of Natural Products®
Nature is considered a prolific source of diverse biologically active chemotypes. While most
reviews have focused on the characteristics of the chemical backbones of natural products …
reviews have focused on the characteristics of the chemical backbones of natural products …
Microbial secondary metabolites: recent developments and technological challenges
Microbial secondary metabolites, like antibiotics, pigments, growth hormones, antitumor
agents, and others, are not essential for the growth and development of microorganism, but …
agents, and others, are not essential for the growth and development of microorganism, but …