Organoids-on-a-chip

SE Park, A Georgescu, D Huh - Science, 2019 - science.org
Recent studies have demonstrated an array of stem cell–derived, self-organizing miniature
organs, termed organoids, that replicate the key structural and functional characteristics of …

Advances in organ-on-a-chip engineering

B Zhang, A Korolj, BFL Lai, M Radisic - Nature Reviews Materials, 2018 - nature.com
Predicting the effects of drugs before human clinical trials is at the heart of drug screening
and discovery processes. The cost of drug discovery is steadily increasing owing to the …

Materials for microfluidic chip fabrication

K Ren, J Zhou, H Wu - Accounts of chemical research, 2013 - ACS Publications
Through manipulating fluids using microfabricated channeland chamber structures,
microfluidics is a powerful tool to realize high sensitive, high speed, high throughput, and …

Engineers are from PDMS-land, Biologists are from Polystyrenia

E Berthier, EWK Young, D Beebe - Lab on a Chip, 2012 - pubs.rsc.org
As the integration of microfluidics into cell biology research proceeds at an ever-increasing
pace, a critical question for those working at the interface of both disciplines is which device …

Microfluidics for cell-based high throughput screening platforms—A review

G Du, Q Fang, JMJ den Toonder - Analytica chimica acta, 2016 - Elsevier
In the last decades, the basic techniques of microfluidics for the study of cells such as cell
culture, cell separation, and cell lysis, have been well developed. Based on cell handling …

Recent advances in nonbiofouling PDMS surface modification strategies applicable to microfluidic technology

A Gokaltun, ML Yarmush, A Asatekin, OB Usta - Technology, 2017 - World Scientific
In the last decade microfabrication processes including rapid prototy** techniques have
advanced rapidly and achieved a fairly mature stage. These advances have encouraged …

A strategy for depositing different types of cells in three dimensions to mimic tubular structures in tissues.

B Yuan, Y **, Y Sun, D Wang, J Sun… - … (Deerfield Beach, Fla …, 2012 - europepmc.org
The fabrication of tubular structures, with multiple cell types forming different layers of the
tube walls, is described using a stress-induced rolling membrane (SIRM). Cell orientation …

Electrochemically driven mechanical energy harvesting

S Kim, SJ Choi, K Zhao, H Yang, G Gobbi… - Nature …, 2016 - nature.com
Efficient mechanical energy harvesters enable various wearable devices and auxiliary
energy supply. Here we report a novel class of mechanical energy harvesters via stress …

Whole-Teflon microfluidic chips

K Ren, W Dai, J Zhou, J Su, H Wu - … of the National Academy of Sciences, 2011 - pnas.org
Although microfluidics has shown exciting potential, its broad applications are significantly
limited by drawbacks of the materials used to make them. In this work, we present a …

A snapshot of microfluidics in point‐of‐care diagnostics: multifaceted integrity with materials and sensors

GA Akceoglu, Y Saylan, F Inci - Advanced Materials …, 2021 - Wiley Online Library
Over four decades, point‐of‐care (POC) technologies and their pivotal applications in the
biomedical arena have increased irrepressibly and allowed to realize the potential of …