Actin dynamics in cell motility, division, and phagocytosis is regulated by complex factors
with multiple feedback loops, often leading to emergent dynamic patterns in the form of …

Macropinocytosis is defined as an actin-dependent but coat-and dynamin-independent
endocytic uptake process, which generates large intracellular vesicles (macropinosomes) …

Macropinocytosis is a conserved endocytic process by which cells engulf droplets of
medium into micron-sized vesicles. We use light-sheet microscopy to define an underlying …

One ubiquitous cellular structure for performing various tasks, such as spreading and
migration over external surfaces, is the sheet-like protrusion called a lamellipodium, which …

Cells often migrate on curved surfaces inside the body, such as curved tissues, blood
vessels, or highly curved protrusions of other cells. Recent in vitro experiments provide clear …

Actin assembly and dynamics are crucial for maintaining cell structure and changing
physiological states. The broad impact of actin on various cellular processes makes it …

The motility of adherent eukaryotic cells is driven by the dynamics of the actin cytoskeleton.
Despite the common force-generating actin machinery, different cell types often show …

Cellular sensing of most environmental cues involves receptors that affect a signal-
transduction excitable network (STEN), which is coupled to a cytoskeletal excitable network …

Macropinocytosis refers to the non-specific uptake of extracellular fluid, which plays
ubiquitous roles in cell growth, immune surveillance, and virus entry. Despite its widespread …

The cellular slime mold Dictyostelium discoideum, a member of the Amoebozoa, has been
extensively studied in cell and developmental biology. D. discoideum is unique in that they …