Alzheimer's disease is a chronic illness with long preclinical and prodromal phases (20
years) and an average clinical duration of 8–10 years. The disease has an estimated …

At present, there may be over 210,000 people with Down syndrome (DS) over the age of 55
in the United States (US) who have significant needs for augmented services due to …

Behavioral and psychological symptoms of dementia (BPSD) are highly prevalent and
represent a significant burden for patients and their caregivers. Early recognition and …

Age-related neurodegenerative diseases (NDDs) are associated with the aggregation and
propagation of specific pathogenic protein species (eg, Aβ, α-synuclein). However, whether …

Background Both pain and challenging behaviour are highly prevalent in dementia, and
multiple studies show that some of these behaviours may be correlated. Pain, especially in …

Abstract Background/Aims: Neuropsychiatric symptoms (NPS) are common in Alzheimer
disease (AD) and vascular dementia (VaD), and are distressful to patients and caregivers …

Alzheimer's disease (AD) and frontotemporal dementia (FTD) are the most common
neurodegenerative earlyonset dementias. Despite the fact that both conditions have a very …

Importance Behavioral and psychological symptoms of dementia (BPSDs) in association
with amnestic and nonamnestic cognitive phenotypes have not been evaluated across …

Abstract Dementia affects approximately 6.5% of people over the age of 65. Whilst cognitive
impairment is central to the dementia concept, neuropsychiatric symptoms are invariably …

Background Although patients with dementia frequently experience neuropsychological
symptoms (NPS) such as agitation, which profoundly impacts patients, caregivers, and the …