Tuberous sclerosis complex (TSC) is a rare genetic disorder caused by mutations in the
TSC1 or TSC2 genes, which encode proteins that antagonise the mammalian isoform of the …

Introduction Nearly one-third of all infants with epilepsy develop drug-resistant epilepsy.
Although epilepsy surgery is a well-established therapy across all age groups, there might …

Objective To assess seizure and cognitive outcomes and their predictors in children (< 16
years at surgery) and adults undergoing temporal lobe epilepsy (TLE) surgery in eight Italian …

OBJECTIVE Pediatric epilepsy surgery is known to be effective, but early surgery in infancy
is not well characterized. Extensive cortical dysplasia, such as hemimegalencephaly, can …

To perform a systematic review evaluating reported outcomes for epilepsy surgery in
pediatric patients with pharmacoresistant epilepsy beyond seizure control, including impact …

The aim of epilepsy treatment is to achieve seizure freedom. Surgery is often still considered
a late option when pharmacological treatments have failed and epilepsy has become drug …

OBJECTIVE Lateral periinsular hemispherotomy (LPH) and vertical parasagittal
hemispherotomy (VPH) are the most popular disconnective techniques for intractable …

OBJECTIVE Surgical treatment of drug-resistant epilepsy originating from the posterior
quadrant (PQ) of the brain often requires large multilobar resections, and disconnective …

Abstract PTEN-induced kinase 1 (PINK1) autophosphorylation-triggered mitophagy is the
main mitophagic pathway in the nervous system. Moreover, multiple studies have confirmed …

Objective The objective of this study was to identify risk factors associated with surgery‐
related neurological morbidity in patients with drug‐resistant epilepsy undergoing …