Role of reactive oxygen species in aging and age-related diseases: A review

MI Anik, N Mahmud, AA Masud, MI Khan… - ACS applied bio …, 2022 - ACS Publications
Research on the role of reactive oxygen species (ROS) in the aging process has advanced
significantly over the last two decades. In light of recent findings, ROS takes part in the aging …

The mechanisms of HBV-induced hepatocellular carcinoma

Y Jiang, Q Han, H Zhao, J Zhang - Journal of hepatocellular …, 2021 - Taylor & Francis
Hepatocellular carcinoma (HCC) is a common malignancy, and the hepatitis B virus (HBV) is
its major pathogenic factor. Over the past decades, it has been confirmed that HBV infection …

PHGDH arginine methylation by PRMT1 promotes serine synthesis and represents a therapeutic vulnerability in hepatocellular carcinoma

K Wang, L Luo, S Fu, M Wang, Z Wang, L Dong… - Nature …, 2023 - nature.com
Serine synthesis is crucial for tumor growth and survival, but its regulatory mechanism in
cancer remains elusive. Here, using integrative metabolomics and transcriptomics analyses …

Reactive oxygen species: Role in carcinogenesis, cancer cell signaling and tumor progression

FL Sarmiento-Salinas, A Perez-Gonzalez… - Life Sciences, 2021 - Elsevier
Cancer is one of the major causes of death in the world and its global burden is expected to
continue increasing. In several types of cancers, reactive oxygen species (ROS) have been …

Cancer metabolism and tumor microenvironment: fostering each other?

Y Yuan, H Li, W Pu, L Chen, D Guo, H Jiang… - Science China Life …, 2022 - Springer
The changes associated with malignancy are not only in cancer cells but also in
environment in which cancer cells live. Metabolic reprogramming supports tumor cell high …

[HTML][HTML] Oxidative stress–induced liver damage and remodeling of the liver vasculature

P Banerjee, N Gaddam, V Chandler… - The American Journal of …, 2023 - Elsevier
As an organ critically important for targeting and clearing viruses, bacteria, and other foreign
material, the liver operates via immune-tolerant, anti-inflammatory mechanisms …

Oxidative stress‐related mechanisms in SARS‐CoV‐2 infections

J Wieczfinska, P Kleniewska… - Oxidative medicine and …, 2022 - Wiley Online Library
The COVID‐19 pandemic caused relatively high mortality in patients, especially in those
with concomitant diseases (ie, diabetes, hypertension, and chronic obstructive pulmonary …

Oxidative stress and redox signaling in the pathophysiology of liver diseases

RGR Mooli, D Mukhi… - Comprehensive …, 2022 - pmc.ncbi.nlm.nih.gov
The increased production of derivatives of molecular oxygen and nitrogen in the form of
reactive oxygen species (ROS) and reactive nitrogen species (RNS) lead to molecular …

Oxidative stress, a trigger of hepatitis C and B virus-induced liver carcinogenesis

AV Ivanov, VT Valuev-Elliston, DA Tyurina… - …, 2016 - pmc.ncbi.nlm.nih.gov
Virally induced liver cancer usually evolves over long periods of time in the context of a
strongly oxidative microenvironment, characterized by chronic liver inflammation and …

[HTML][HTML] Role of selenium in viral infections with a major focus on SARS-CoV-2

SS Martinez, Y Huang, L Acuna, E Laverde… - International Journal of …, 2021 - mdpi.com
Viral infections have afflicted human health and despite great advancements in scientific
knowledge and technologies, continue to affect our society today. The current coronavirus …