This review encompasses the most important advances in liver functions and hepatotoxicity
and analyzes which mechanisms can be studied in vitro. In a complex architecture of nested …

Breast cancer staging and treatment are possible during pregnancy, and should be defined
in a multidisciplinary setting. Tumour biology, tumour stage, and gestational stage at …

The heavy metals mercury, lead, and cadmium are toxicants, which are well-known to cross
the placenta and to accumulate in fetal tissues. Prenatal exposure to mercury and lead …

Studies on the increasing number of transporters found in the placental barrier are gaining
momentum, because of their tissue‐specific expression, significance in physiology and …

Early human life is considered a critical window of susceptibility to external exposures.
Infants are exposed to a multitude of environmental factors, collectively referred to as the …

The placenta is a critical organ during pregnancy, essential for the provision of an optimal
intrauterine environment, with fetal survival, growth, and development relying on correct …

Bisphenol A (BPA), an estrogen-like chemical, leaches from consumer products potentially
causing human exposure. To examine the effects of BPA exposure during pregnancy, we …

Pathologies associated with uteroplacental hypoxia, such as preeclampsia are among the
leading causes of maternal and perinatal morbidity in the world. Its fundamental …

The human placenta fulfills a variety of essential functions during prenatal life. Several ABC
transporters are expressed in the human placenta, where they play a role in the transport of …

Although various drugs, environmental pollutants and nanoparticles (NP) can cross the
human placental barrier and may harm the develo** fetus, knowledge on predictive …