A guide to immunotherapy for COVID-19

FL van de Veerdonk, E Giamarellos-Bourboulis… - Nature medicine, 2022 - nature.com
Immune dysregulation is an important component of the pathophysiology of COVID-19. A
large body of literature has reported the effect of immune-based therapies in patients with …

[HTML][HTML] Immunopathology of Hyperinflammation in COVID-19

JN Gustine, D Jones - The American journal of pathology, 2021 - Elsevier
The rapid spread of coronavirus disease 2019 (COVID-19), caused by severe acute
respiratory syndrome–coronavirus 2 (SARS-CoV-2), has resulted in an unprecedented …

Characteristics and outcomes of US children and adolescents with multisystem inflammatory syndrome in children (MIS-C) compared with severe acute COVID-19

LR Feldstein, MW Tenforde, KG Friedman, M Newhams… - Jama, 2021 - jamanetwork.com
Importance Refinement of criteria for multisystem inflammatory syndrome in children (MIS-C)
may inform efforts to improve health outcomes. Objective To compare clinical characteristics …

Multisystem inflammatory syndrome in children related to COVID-19: a systematic review

L Hoste, R Van Paemel, F Haerynck - European journal of pediatrics, 2021 - Springer
An association between a novel pediatric hyperinflammatory condition and SARS-CoV-2
was recently published and termed pediatric inflammatory multisystem syndrome, temporally …

[HTML][HTML] Multisystem inflammatory syndrome in children: a systematic review

M Ahmed, S Advani, A Moreira, S Zoretic… - …, 2020 - thelancet.com
Background Multisystem inflammatory syndrome in children (MIS-C), also known as
pediatric inflammatory multisystem syndrome, is a new dangerous childhood disease that is …

Multisystem inflammatory syndrome in children—initial therapy and outcomes

MBF Son, N Murray, K Friedman… - … England Journal of …, 2021 - Mass Medical Soc
Background The assessment of real-world effectiveness of immunomodulatory medications
for multisystem inflammatory syndrome in children (MIS-C) may guide therapy. Methods We …

American College of rheumatology clinical guidance for multisystem inflammatory syndrome in children associated with SARS–CoV‐2 and Hyperinflammation in …

LA Henderson, SW Canna, KG Friedman… - Arthritis & …, 2021 - Wiley Online Library
Objective To provide guidance on the management of Multisystem Inflammatory Syndrome
in Children (MIS‐C), a condition characterized by fever, inflammation, and multiorgan …

[HTML][HTML] Multisystem inflammatory syndrome in children and Kawasaki disease: a critical comparison

C Sharma, M Ganigara, C Galeotti, J Burns… - Nature Reviews …, 2021 - nature.com
Children and adolescents infected with severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) are predominantly asymptomatic or have mild symptoms compared with the …

Severe COVID-19, multisystem inflammatory syndrome in children, and Kawasaki disease: immunological mechanisms, clinical manifestations and management

J Kabeerdoss, RK Pilania, R Karkhele… - Rheumatology …, 2021 - Springer
Multisystem inflammatory syndrome (MIS-C) is a pediatric hyperinflammation disorder
caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). It has now been …

Local and systemic responses to SARS-CoV-2 infection in children and adults

M Yoshida, KB Worlock, N Huang, RGH Lindeboom… - Nature, 2022 - nature.com
It is not fully understood why COVID-19 is typically milder in children,–. Here, to examine the
differences between children and adults in their response to SARS-CoV-2 infection, we …