Herpesviruses infect virtually all humans and establish lifelong latency and reactivate to
infect other humans. Latency requires multiple functions: maintaining the herpesvirus …

Epstein-Barr virus (EBV) is a ubiquitous gammaherpesvirus which asymptomatically infects
the majority of the world population. Under immunocompromised conditions, EBV can …

Human papillomaviruses (HPV) are a large family of viruses which contain a circular, double-
stranded DNA genome of approximately 8000 base pairs. The viral DNA is chromatinized by …

Worldwide, one fifth of cancers in the population are associated with viral infections. Among
them, gammaherpesvirus, specifically HHV4 (EBV) and HHV8 (KSHV), are two oncogenic …

Much of the HSV-1 life cycle is carried out in the cell nucleus, including the expression,
replication, repair, and packaging of viral genomes. Viral proteins, as well as cellular factors …

Epstein-Barr virus (EBV) genomes persist in latently infected cells as extrachromosomal
episomes that attach to host chromosomes through the tethering functions of EBNA1, a viral …

The complex life cycle of oncogenic human papillomavirus (HPV) initiates in undifferentiated
basal epithelial keratinocytes where expression of the E6 and E7 oncogenes is restricted …

The Epstein-Barr virus (EBV) nuclear antigen leader protein (EBNA-LP) is the first viral
latency-associated protein produced after EBV infection of resting B cells. Its role in B cell …

Nasopharyngeal carcinoma (NPC) is a distinct type of head and neck cancer that is highly
associated with Epstein-Barr virus (EBV) infection. EBV acts as an epigenetic driver in NPC …

Epstein–Barr Virus (EBV) is a human gamma-herpesvirus that is widespread worldwide. To
this day, about 200,000 cancer cases per year are attributed to EBV infection. EBV is …