The transforming growth factor β (TGF-β) family of growth factors control the development
and homeostasis of most tissues in metazoan organisms. Work over the past few years has …

The recent identification of the SMAD family of signal transducer proteins has unravelled the
mechanisms by which transforming growth factor-β (TGF-β) signals from the cell membrane …

Simultaneous recordings were made from large ensembles of hippocampal" place cells" in
three rats during spatial behavioral tasks and in slow-wave sleep preceding and following …

Epithelial and hematopoietic cells have a high turnover and their progenitor cells divide
continuously, making them prime targets for genetic and epigenetic changes that lead to cell …

This second edition of the Bone Mechanics Handbook summarizes the current
understanding of bone mechanics with comprehensive coverage of the histology …

Tendons are able to respond to mechanical forces by altering their structure, composition,
and mechanical properties—a process called tissue mechanical adaptation. The fact that …

The secreted polypeptide transforming growth factor-beta (TGF-beta) exerts its multiple
activities through type I and II cell surface receptors. In epithelial cells, activation of the TGF …

Exogenous addition of neutralising antibody to transforming growth factor-β1, 2 to cutaneous
wounds in adult rodents reduces scarring. Three isoforms of transforming growth factor-β (1 …

We have analysed the interactions of three proteoglycans of the decorin family, decorin,
biglycan and fibromodulin, with transforming growth factor beta (TGF-beta). The …

Targeted mutation of TGFβ1 in mice demonstrated that TGFβ1 is one of the key negative
regulators of immune homeostasis, as its absence leads to activation of a self-targeted …