Sex differences in psychiatric disorders: what we can learn from sex chromosome aneuploidies

T Green, S Flash, AL Reiss - Neuropsychopharmacology, 2019 - nature.com
The study of sexual dimorphism in psychiatric and neurodevelopmental disorders is
challenging due to the complex interplay of diverse biological, psychological, and social …

Opportunities, barriers, and recommendations in Down syndrome research

JA Hendrix, A Amon, L Abbeduto… - … science of rare …, 2021 - journals.sagepub.com
BACKGROUND: Recent advances in medical care have increased life expectancy and
improved the quality of life for people with Down syndrome (DS). These advances are the …

A review of neurocognitive functioning and risk for psychopathology in sex chromosome trisomy (47, XXY, 47, XXX, 47, XYY)

S van Rijn - Current opinion in psychiatry, 2019 - journals.lww.com
The research field of SCT is in need of a more longitudinal perspective to identify early
markers of 'at risk'development, and to assess the effectiveness of early interventions …

Adaptive behaviour, executive function and employment in adults with Down syndrome

B Tomaszewski, D Fidler, D Talapatra… - Journal of Intellectual …, 2018 - Wiley Online Library
Abstract Background Individuals with Down syndrome (DS) demonstrate difficulties with
aspects of executive function (EF) and adaptive behaviour across the lifespan. There is a …

A cross‐sectional analysis of executive function in Down syndrome from 2 to 35 years

SJ Loveall, FA Conners, AS Tungate… - Journal of …, 2017 - Wiley Online Library
Background Previous research has indicated a unique profile of executive function (EF) in
children and adolescents with Down syndrome (DS). However, there is a paucity of research …

Executive function in Down syndrome: A meta-analysis

AS Tungate, FA Conners - Research in developmental disabilities, 2021 - Elsevier
Background Executive function (EF) refers to a set of cognitive processes involved in goal-
oriented behavior—especially inhibition, attention shifting, and working memory. EF has …

Cognitive functioning in children with Down syndrome: Current knowledge and future directions

AF Lukowski, HM Milojevich, L Eales - Advances in child development and …, 2019 - Elsevier
Infants and children with Down syndrome (DS) can look forward toward bright futures, as
individuals with DS are living healthier, more productive lives than ever due to medical …

Alterations of specific cortical GABAergic circuits underlie abnormal network activity in a mouse model of Down syndrome

J Zorrilla de San Martin, C Donato, J Peixoto, A Aguirre… - Elife, 2020 - elifesciences.org
Down syndrome (DS) results in various degrees of cognitive deficits. In DS mouse models,
recovery of behavioral and neurophysiological deficits using GABAAR antagonists led to …

Executive functions and adaptive behaviour in individuals with Down syndrome

S Onnivello, S Colaianni, F Pulina… - Journal of …, 2022 - Wiley Online Library
Background Previous research has explored executive functions (EFs) and adaptive
behaviour in children and adolescents with Down syndrome (DS), but there is a paucity of …

Altered gut microbiota composition is associated with difficulty in explicit emotion regulation in young children

H Fujihara, M Matsunaga, E Ueda, T Kajiwara… - Microorganisms, 2023 - mdpi.com
Executive function (EF) consists of explicit emotion regulation (EER) and cognitive control
(CC). Childhood EER in particular predicts mental and physical health in adulthood …