Gliomas, a prevalent category of primary malignant brain tumors, pose formidable clinical
challenges due to their invasive nature and limited treatment options. The current …

Glioblastoma multiforme (GBM) is the most common and malignant type of primary brain
tumor in adults. Despite important advances in understanding the molecular pathogenesis …

For decades, great strides have been made in the field of immunometabolism. A plethora of
evidence ranging from basic mechanisms to clinical transformation has gradually embarked …

Glioblastoma, the most aggressive and common malignant primary brain tumour, is
characterized by infiltrative growth, abundant vascularization, and aggressive clinical …

The α-tubulin subtype, Tubulin α-1b chain (TUBA1B), has been shown to influence immune
cell infiltration, cancer growth, and survival across various malignancies. However, a …

Glioma is a type of aggressive and incurable brain tumor. Patients with glioma are highly
resistant to all types of therapies, including immunotherapies. Epigenetic reprogramming is …

Gliomas are the most common primary tumors of the central nervous system, with
glioblastoma multiforme (GBM) having the highest incidence, and their therapeutic efficacy …

Background Glioblastoma multiforme (GBM) is a highly aggressive primary brain tumor, that
is refractory to standard treatment and to immunotherapy with immune-checkpoint inhibitors …

The search for reliable protein biomarker candidates is critical for early disease detection
and treatment. However, current immunoassay technologies are failing to meet increasing …

Glioma, an aggressive type of brain tumors of glial origin is highly heterogeneous, posing
significant treatment challenges due to its intrinsic resistance to conventional therapeutic …