Strategies to reduce the risks of mRNA drug and vaccine toxicity
Abstract mRNA formulated with lipid nanoparticles is a transformative technology that has
enabled the rapid development and administration of billions of coronavirus disease 2019 …
enabled the rapid development and administration of billions of coronavirus disease 2019 …
Advanced tandem mass spectrometry in metabolomics and lipidomics—methods and applications
S Heiles - Analytical and Bioanalytical Chemistry, 2021 - Springer
Metabolomics and lipidomics are new drivers of the omics era as molecular signatures and
selected analytes allow phenotypic characterization and serve as biomarkers, respectively …
selected analytes allow phenotypic characterization and serve as biomarkers, respectively …
Ozone-enabled fatty acid discovery reveals unexpected diversity in the human lipidome
Fatty acid isomers are responsible for an under-reported lipidome diversity across all
kingdoms of life. Isomers of unsaturated fatty acids are often masked in contemporary …
kingdoms of life. Isomers of unsaturated fatty acids are often masked in contemporary …
Deep-profiling of phospholipidome via rapid orthogonal separations and isomer-resolved mass spectrometry
T ** by mass spectrometry: recent technical advances and applications
In-depth structural characterization of lipids is an essential component of lipidomics. There
has been a rapid expansion of mass spectrometry methods that are capable of resolving …
has been a rapid expansion of mass spectrometry methods that are capable of resolving …
Roles of palmitoleic acid and its positional isomers, hypogeic and sapienic acids, in inflammation, metabolic diseases and cancer
MA Bermúdez, L Pereira, C Fraile, L Valerio… - Cells, 2022 - mdpi.com
In the last few years, the monounsaturated hexadecenoic fatty acids are being increasingly
considered as biomarkers of health with key functions in physiology and pathophysiology …
considered as biomarkers of health with key functions in physiology and pathophysiology …
Mass spectrometry imaging of lipids with isomer resolution using high-pressure ozone-induced dissociation
Mass spectrometry imaging (MSI) of lipids within tissues has significant potential for both
biomolecular discovery and histopathological applications. Conventional MSI technologies …
biomolecular discovery and histopathological applications. Conventional MSI technologies …
Inhibition of cannabinoid receptor type 1 sensitizes triple-negative breast cancer cells to ferroptosis via regulating fatty acid metabolism
Triple-negative breast cancer (TNBC) is a heterogeneous subtype of breast cancer that
displays highly aggressive with poor prognosis. Owing to the limited targets and drugs for …
displays highly aggressive with poor prognosis. Owing to the limited targets and drugs for …
A new update of MALDI-TOF mass spectrometry in lipid research
KM Engel, P Prabutzki, J Leopold, A Nimptsch… - Progress in lipid …, 2022 - Elsevier
Matrix-assisted laser desorption and ionization (MALDI) mass spectrometry (MS) is an
indispensable tool in modern lipid research since it is fast, sensitive, tolerates sample …
indispensable tool in modern lipid research since it is fast, sensitive, tolerates sample …
[HTML][HTML] Mitochondrial and metabolic alterations in cancer cells
J Di Gregorio, S Petricca, R Iorio, E Toniato… - European journal of cell …, 2022 - Elsevier
Metabolic alterations have been observed in many cancer types. The deregulated
metabolism has thus become an emerging hallmark of the disease, where the metabolism is …
metabolism has thus become an emerging hallmark of the disease, where the metabolism is …