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Acid hydrazides, potent reagents for synthesis of oxygen-, nitrogen-, and/or sulfur-containing heterocyclic rings
Heterocycles form by far the largest of the classical divisions of organic chemistry. Moreover,
they are of immense importance not only both biologically and industrially but also to the …
they are of immense importance not only both biologically and industrially but also to the …
1, 2, 4-triazine analogs as novel class of therapeutic agents
1, 2, 4-Triazine nucleus is a prominent structural core system present in numerous
pharmacologically active compounds. Till date, various 1, 2, 4-triazine analogs, possesing a …
pharmacologically active compounds. Till date, various 1, 2, 4-triazine analogs, possesing a …
Synthesis and radical scavenging activity of new phenolic hydrazone/hydrazide derivatives: Experimental and theoretical studies
Hydrazone and hydrazone-hydrazide-based compounds represent important classes of
compounds that continue to attract increasing interest due to their diverse pharmacological …
compounds that continue to attract increasing interest due to their diverse pharmacological …
Antioxidant activity of novel imidazo [2, 1-b] thiazole derivatives: Design, synthesis, biological evaluation, molecular docking study and in silico ADME prediction
A series of novel oxo-hydrazone and spirocondensed-thiazolidine derivatives of imidazo [2,
1-b] thiazole were synthesized and evaluated for their antioxidant activity. The antioxidant …
1-b] thiazole were synthesized and evaluated for their antioxidant activity. The antioxidant …
Design and synthesis of novel Imidazo [2, 1-b] thiazole derivatives as potent antiviral and antimycobacterial agents
A series of novel acyl-hydrazone (4a-d) and spirothiazolidinone (5a-d, 6a-d) derivatives of
imidazo [2, 1-b] thiazole were synthesized and evaluated for their antiviral and …
imidazo [2, 1-b] thiazole were synthesized and evaluated for their antiviral and …
[HTML][HTML] Synthesis and investigation of antimicrobial activities of nitrofurazone analogues containing hydrazide-hydrazone moiety
Ł Popiołek, A Biernasiuk - Saudi Pharmaceutical Journal, 2017 - Elsevier
In this research we synthesized and tested for in vitro antimicrobial activity 21 nitrofurazone
analogues. The compounds we obtained were identified on the basis of 1 H NMR and 13 C …
analogues. The compounds we obtained were identified on the basis of 1 H NMR and 13 C …
Benzimidazole-derived carbohydrazones as dual monoamine oxidases and acetylcholinesterase inhibitors: design, synthesis, and evaluation
A series of novel benzimidazole-derived carbohydrazones was designed, synthesized and
evaluated for their dual inhibition potential against monoamine oxidases (MAOs) and …
evaluated for their dual inhibition potential against monoamine oxidases (MAOs) and …
Analgesic, anti‐inflammatory, and antiplatelet profile of hydrazones containing synthetic molecules
Hydrazones are present in many of the bioactive compounds with wide interest because of
their diverse pharmacological applications. Hydrazones possess wide variety of biological …
their diverse pharmacological applications. Hydrazones possess wide variety of biological …
Synthesis, anticancer and antioxidant activities of novel heterocyclic phenolic hydrazone based derivatives: Investigation of DFT calculation, molecular docking and …
A **ng, P Zhu, B Zhang, J Lu, Y Zhang, D Zeng… - Journal of Molecular …, 2025 - Elsevier
In this research, the anticancer and antioxidant activities of a novel class of heterocyclic
phenolic hydrazone derivatives were investigated. The structure determination of the …
phenolic hydrazone derivatives were investigated. The structure determination of the …
[HTML][HTML] Synthesis, characterization, single-crystal X-ray structure and biological activities of [(Z)-N′-(4-methoxybenzylidene) benzohydrazide–nickel (II)] Complex
(Z)-N′-(4-methoxybenzylidene) benzohydrazide (HL) and its Ni (II) complex (Ni (II)-2L)
were synthesized using eco-friendly protocols. The single X-ray crystal structure of Ni (II)-2L …
were synthesized using eco-friendly protocols. The single X-ray crystal structure of Ni (II)-2L …