Interstitial lung diseases
Over 200 interstitial lung diseases, from ultra rare to relatively common, are recognised.
Most interstitial lung diseases are characterised by inflammation or fibrosis within the …
Most interstitial lung diseases are characterised by inflammation or fibrosis within the …
Treatment of fibrotic interstitial lung disease: current approaches and future directions
Fibrotic interstitial lung disease (ILD) represents a large group of pulmonary disorders that
are often progressive and associated with high morbidity and early mortality. Important …
are often progressive and associated with high morbidity and early mortality. Important …
Cyclophosphamide added to glucocorticoids in acute exacerbation of idiopathic pulmonary fibrosis (EXAFIP): a randomised, double-blind, placebo-controlled, phase …
Background The use of cyclophosphamide in patients with acute exacerbation of idiopathic
pulmonary fibrosis (IPF) is unknown. Our study was designed to evaluate the efficacy and …
pulmonary fibrosis (IPF) is unknown. Our study was designed to evaluate the efficacy and …
Longitudinal lung function and gas transfer in individuals with idiopathic pulmonary fibrosis: a genome-wide association study
Background Idiopathic pulmonary fibrosis (IPF) is an incurable lung disease characterised
by progressive scarring leading to alveolar stiffness, reduced lung capacity, and impeded …
by progressive scarring leading to alveolar stiffness, reduced lung capacity, and impeded …
Therapeutic targeting of the respiratory microbiome
Culture-independent microbiology has transformed our understanding of the respiratory
microbiome in health and disease (1). Enabled by advances in next-generation sequencing …
microbiome in health and disease (1). Enabled by advances in next-generation sequencing …
The microbiome: an integral player in immune homeostasis and inflammation in the respiratory tract
The last decade of microbiome research has highlighted its fundamental role in systemic
immune and metabolic homeostasis. The microbiome plays a prominent role during …
immune and metabolic homeostasis. The microbiome plays a prominent role during …
Meaningful Endpoints for Idiopathic Pulmonary Fibrosis (IPF) Clinical Trials: Emphasis on 'Feels, Functions, Survives'. Report of a Collaborative Discussion in a …
G Raghu, M Ghazipura, TR Fleming… - American journal of …, 2024 - atsjournals.org
Background: Idiopathic pulmonary fibrosis (IPF) carries significant mortality and
unpredictable progression, with limited therapeutic options. Designing trials with patient …
unpredictable progression, with limited therapeutic options. Designing trials with patient …
Interstitial Lung Disease: A Review
TM Maher - JAMA, 2024 - jamanetwork.com
Importance Interstitial lung disease (ILD) consists of a group of pulmonary disorders
characterized by inflammation and/or fibrosis of the lung parenchyma associated with …
characterized by inflammation and/or fibrosis of the lung parenchyma associated with …
Targeting growth factor and cytokine pathways to treat idiopathic pulmonary fibrosis
H Ma, S Liu, S Li, Y **a - Frontiers in Pharmacology, 2022 - frontiersin.org
Idiopathic pulmonary fibrosis (IPF) is a chronic interstitial lung disease of unknown origin
that usually results in death from secondary respiratory failure within 2–5 years of diagnosis …
that usually results in death from secondary respiratory failure within 2–5 years of diagnosis …
Lung microbiome in idiopathic pulmonary fibrosis and other interstitial lung diseases
Interstitial lung diseases represent a heterogeneous and wide group of diseases in which
factors leading to disease initiation and progression are not fully understood. Recent …
factors leading to disease initiation and progression are not fully understood. Recent …